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Substance Name: Styrene
RN: 100-42-5
UNII: 44LJ2U959V
InChIKey: PPBRXRYQALVLMV-UHFFFAOYSA-N

Note

  • A colorless, toxic liquid with a strong aromatic odor. It is used to make rubbers, polymers and copolymers, and polystyrene plastics.

Molecular Formula

  • C8-H8

Molecular Weight

  • 104.151
 

Classification Codes

Classification Codes

  • Human Data
  • Mutation Data
  • Reproductive Effect
  • Skin / Eye Irritant
  • Tumor Data

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 271
  • 2011 CERCLA Priority List, Rank: 273
  • Overall Carcinogenic Evaluation: Group 2B
  • Reportable Quantity (RQ) = 1000 lb
  • TWA (20 ppm); STEL (40 ppm); Not classifiable as a human carcinogen; BEI
  • TWA 100 mg/m3; Ceiling 200 mg/m3, peak 300 in 5 min in any

Names and Synonyms

Name of Substance

  • Styrene

MeSH Heading

  • Styrene

Synonyms

  • AI3-24374
  • Benzene, vinyl-
  • Bulstren K-525-19
  • CCRIS 564
  • Cinnamene
  • EC 202-851-5
  • EINECS 202-851-5
  • Ethenylbenzene
  • Ethylene, phenyl-
  • FEMA No. 3233
  • FEMA Number 3234
  • HSDB 171
  • NCI-C02200
  • NSC 62785
  • Phenethylene
  • Phenylethene
  • Phenylethylene
  • Stirolo
  • Stirolo [Italian]
  • Styreen
  • Styreen [Dutch]
  • Styren
  • Styren [Czech]
  • Styrene
  • Styrene monomer
  • Styrol
  • Styrol [German]
  • Styrole
  • Styrolene
  • Styropol SO
  • UNII-44LJ2U959V
  • Vinyl benzene
  • Vinylbenzen
  • Vinylbenzen [Czech]
  • Vinylbenzen [Dutch]
  • Vinylbenzene
  • Vinylbenzol

Systematic Names

  • Benzene, ethenyl-
  • Styrene

Superlist Names

  • Benzene, ethenyl-
  • Phenylethylene
  • Phenylethylene, inhibited
  • Styrene
  • Styrene (monomer)
  • Styrene monomer
  • Styrene monomer, inhibited
  • Styrene monomer, inhibited [UN2055] [Flammable liquid]
  • UN2055
  • Vinyl benzene
  • Vinylbenzene, inhibited

Registry Numbers

CAS Registry Number

  • 100-42-5

FDA UNII

  • 44LJ2U959V

Other Registry Numbers

  • 1161074-30-1
  • 1198090-46-8
  • 79637-11-9

System Generated Number

  • 0000100425

Structure Descriptors

InChI

1S/C8H8/c1-2-8-6-4-3-5-7-8/h2-7H,1H2

InChIKey

PPBRXRYQALVLMV-UHFFFAOYSA-N

Smiles

c1(ccccc1)C=C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LCLo inhalation 12gm/m3/14H (12000mg/m3) BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: ANTIPSYCHOTIC

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
Journal of Industrial Hygiene and Toxicology. Vol. 24, Pg. 295, 1942.
human LCLo inhalation 10000ppm/30M (10000ppm)   "Practical Toxicology of Plastics," Lefaux, R., Cleveland, OH, Chemical Rubber Co., 1968Vol. -, Pg. 77, 1968.
human TCLo inhalation 20ug/m3 (0.02mg/m3) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 26(8), Pg. 11, 1961.
human TCLo inhalation 376ppm/1H (376ppm) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)
Archives of Environmental Health. Vol. 16, Pg. 656, 1968.
human TCLo inhalation 600ppm (600ppm) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
AMA Archives of Industrial Health. Vol. 14, Pg. 387, 1956.
mammal (species unspecified) LD50 oral > 1500mg/kg (1500mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(4), Pg. 86, 1974.
mouse LC50 inhalation 9500mg/m3/4H (9500mg/m3)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 106, 1982.
mouse LD50 intraperitoneal 660mg/kg (660mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 617, 1969.
mouse LD50 intravenous 90mg/kg (90mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 617, 1969.
mouse LD50 oral 316mg/kg (316mg/kg)   Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. Vol. NCI-E-C-72-3252, Pg. 1973,
rabbit LCLo inhalation 4000ppm/4H (4000ppm)   Union Carbide Data Sheet. Vol. 12/13/1963,
rat LC50 inhalation 12gm/m3/4H (12000mg/m3)   Archives of Environmental Health. Vol. 18, Pg. 878, 1969.
rat LD50 intraperitoneal 898mg/kg (898mg/kg)   Environmental Research. Vol. 40, Pg. 411, 1986.
rat LD50 oral 2650mg/kg (2650mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LIVER: OTHER CHANGES
Science Reports of the Research Institutes, Tohoku University, Series C: Medicine. Vol. 36(1-4), Pg. 10, 1989.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -3.10E+01 deg C   EXP
Boiling Point 145 deg C   EXP
log P (octanol-water) 2.95 (none)   EXP
Water Solubility 310 mg/L 25 EXP
Vapor Pressure 6.4 mm Hg 25 EXP
Henry's Law Constant 0.00275 atm-m3/mole 25 EXP
Atmospheric OH Rate Constant 5.80E-11 cm3/molecule-sec 25 EXP

Physical property data is provided to ChemIDplus by SRC, Inc.