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Substance Name: FOLFIRI Regimen
RN: 1000669-05-5
InChIKey: JYEFSHLLTQIXIO-SMNQTINBSA-N

Note

  • NCI: A chemotherapy regimen consisting of leucovorin calcium (calcium folinate), 5-fluorouracil, and irinotecan used in the treatment of advanced-stage and metastatic colorectal cancer. (NCI Thesaurus)

Classification Code

  • Antineoplastic Agents

Molecular Formula

  • C33-H38-N4-O6.C20-H23-N7-O7.C4-H3-F-N2-O2

Molecular Weight

  • 1190.2066
 
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Names and Synonyms

Results Name

  • FOLFIRI Regimen

Name of Substance

  • 5-Fluorouracil mixture with Folinic acid and Irinotecan

Synonyms

  • 5-Fluorouracil / Folinic acid / irinotecan
  • 5-Fluorouracil mixture with Folinic acid and Irinotecan
  • FOLFIRI
  • FOLFIRI Regimen
  • Folinic acid / 5-fluorouracil / irinotecan
  • Irinotecan, Leucovorin and Fluorouracil mixture

Systematic Name

  • L-Glutamic acid, N-(4-(((2-amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl) methyl)amino)benzoyl)-, mixt. with (4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-9-yl (1,4'-bipiperidine)-1'-carboxylate and 5-fluoro-2,4(1H,3H)-pyrimidinedione

Registry Numbers

CAS Registry Number

  • 1000669-05-5

System Generated Number

  • 1000669055

Molecular Formulas

Molecular Formula

  • C33-H38-N4-O6.C20-H23-N7-O7.C4-H3-F-N2-O2

Molecular Formula Fragments

  • C20-H23-N7-O7
  • C33-H38-N4-O6
  • C4-H3-F-N2-O2
  • COMPONENT

Structure Descriptors

InChI

1S/C33H38N4O6.C20H23N7O7.C4H3FN2O2/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26,41)4-2;21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30;5-2-1-6-4(9)7-3(2)8/h8-9,16-17,20,41H,3-7,10-15,18-19H2,1-2H3;1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32);1H,(H2,6,7,8,9)/t33-;12?,13-;/m00./s1

InChIKey

JYEFSHLLTQIXIO-SMNQTINBSA-N

Smiles

C([C@@H](C(=O)O)NC(=O)c1ccc(cc1)NCC1CNc2c(N1C=O)c(=O)nc([nH]2)N)CC(=O)O.c1(=O)[nH]cc(c(=O)[nH]1)F.c12c([C@@](C(=O)OC1)(O)CC)cc1n(c2=O)Cc2c1nc1c(c2CC)cc(cc1)OC(=O)N1CCC(CC1)N1CCCCC1