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Substance Name: Sotatercept [USAN:INN]
RN: 1001080-50-7


  • A dimeric fusion protein consisting of the extracellular domain of the human ActRIIA linked to the Fc portion of human IgG1 and may be an effective therapy in a variety of diseases involving bone loss.

Molecular Formula

  • Unspecified

Classification Code

  • Red Cell Maturation Agent for the Treatment of Anemia, and Bone Anabolic Agent for the Treatment of Cancer-Related Bone Loss
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Names and Synonyms

Name of Substance

  • Sotatercept [USAN:INN]


  • ACE 011
  • ACE-011
  • ACE011
  • Sotatercept
  • UNII-0QI90BTJ37

Systematic Name

  • Activin receptor type IIA (synthetic human extracellular domain-containing fragment) fusion protein with immunoglobulin G1 (synthetic human heavy chain Fc fragment), dimer

Registry Numbers

CAS Registry Number

  • 1001080-50-7


  • 0QI90BTJ37

System Generated Number

  • 1001080507