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Substance Name: Ozone
RN: 10028-15-6
UNII: 66H7ZZK23N
InChIKey: CBENFWSGALASAD-UHFFFAOYSA-N

Note

  • The unstable triatomic form of oxygen, O3. It is a powerful oxidant that is produced for various chemical and industrial uses. Its production is also catalyzed in the ATMOSPHERE by ULTRAVIOLET RAY irradiation of oxygen or other ozone precursors such as VOLATILE ORGANIC COMPOUNDS and NITROGEN OXIDES. About 90% of the ozone in the atmosphere exists in the stratosphere (STRATOSPHERIC OZONE).

Molecular Formula

  • O3

Molecular Weight

  • 47.997
 

Classification Codes

Classification Codes

  • Air Pollutants
  • Antiviral (COVID-19)
  • Environmental Pollutants
  • Human Data
  • Mutation Data
  • Noxae
  • Oxidants
  • Oxidants, Photochemical
  • Reproductive Effect
  • Skin / Eye Irritant
  • Tumor Data

Superlist Classification Codes

  • Threshold Planning Quantity (TPQ) = 100 lb
  • TWA (0.05 ppm heavy work; 0.08 ppm moderate work; 0.10 ppm light work; 0.20 ppm heavy, moderate or light workloads (<2 hours)); Not classifiable as a human carcinogen
  • TWA 0.1 ppm (0.2 mg/m3)

Names and Synonyms

Name of Substance

  • Ozone

MeSH Heading

  • Ozone

Synonyms

  • CCRIS 4503
  • EINECS 233-069-2
  • HSDB 717
  • Oxygen, mol (O3)
  • Ozon
  • Ozon [Polish]
  • Ozone
  • Ozone heavy work
  • Triatomic oxygen
  • UNII-66H7ZZK23N

Systematic Name

  • Ozone

Superlist Names

  • Ozone
  • Ozone heavy, moderate, or light workloads (<2 hours)
  • Ozone light work
  • Ozone moderate work

Registry Numbers

CAS Registry Number

  • 10028-15-6

FDA UNII

  • 66H7ZZK23N

Other Registry Numbers

  • 412908-40-8
  • 728855-47-8
  • 74087-86-8
  • 855426-80-1

System Generated Number

  • 0010028156

Structure Descriptors

InChI

InChI=1S/O3/c1-3-2

InChIKey

CBENFWSGALASAD-UHFFFAOYSA-N

Smiles

[O-][O+]=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LC50 inhalation 34500ppb/3H (34.5ppm) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 Industrial Medicine and Surgery. Vol. 25, Pg. 301, 1956.
guinea pig LC50 inhalation 24800ppb/3H (24.8ppm) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Industrial Medicine and Surgery. Vol. 26, Pg. 63, 1957.
hamster LC50 inhalation 10500ppb/4H (10.5ppm)   AMA Archives of Industrial Health. Vol. 15, Pg. 181, 1957.
human LCLo inhalation 50ppm/30M (50ppm) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

BEHAVIORAL: HEADACHE		 "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 446, 1969.
human TCLo inhalation 200ppb/4H/4D- (0.2ppm) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

CARDIAC: PULSE RATE 		American Journal of Respiratory and Critical Care Medicine. Vol. 161, Pg. 1855, 2000.
human TCLo inhalation 600ppb/2H (0.6ppm) LUNGS, THORAX, OR RESPIRATION: COUGH

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 American Review of Respiratory Disease. Vol. 118, Pg. 287, 1978.
human TCLo inhalation 1ppm (1ppm) LUNGS, THORAX, OR RESPIRATION: COUGH

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Archives of Environmental Health. Vol. 10, Pg. 295, 1965.
human TCLo inhalation 100ppm/1M (100ppm) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"		 News Edition, American Chemical Society. Vol. 19, Pg. 686, 1941.
man TCLo inhalation 80ppb/6.6H (0.08ppm) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: COUGH

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION		 Archives of Environmental Health. Vol. 46, Pg. 145, 1991.
man TCLo inhalation 1860ppb/75M (1.86ppm) LUNGS, THORAX, OR RESPIRATION: COUGH

CARDIAC: PULSE RATE

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE		 Archives of Environmental Health. Vol. 10, Pg. 517, 1965.
mouse LC50 inhalation 12600ppb/3H (12.6ppm) BLOOD: HEMORRHAGE

LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA		 Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 16, Pg. 22, 1957.
rabbit LC50 inhalation 36ppm/3H (36ppm) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)		 Industrial Medicine and Surgery. Vol. 25, Pg. 301, 1956.
rat LC50 inhalation 4800ppb/4H (4.8ppm) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

BLOOD: HEMORRHAGE		 AMA Archives of Industrial Health. Vol. 15, Pg. 181, 1957.
women TCLo inhalation 350ppb/75M (0.35ppm) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 Inhalation Toxicology. Vol. 12, Pg. 151, 2000.