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Substance Name: Ozone
RN: 10028-15-6
UNII: 66H7ZZK23N
InChIKey: CBENFWSGALASAD-UHFFFAOYSA-N
Note
- The unstable triatomic form of oxygen, O3. It is a powerful oxidant that is produced for various chemical and industrial uses. Its production is also catalyzed in the ATMOSPHERE by ULTRAVIOLET RAY irradiation of oxygen or other ozone precursors such as VOLATILE ORGANIC COMPOUNDS and NITROGEN OXIDES. About 90% of the ozone in the atmosphere exists in the stratosphere (STRATOSPHERIC OZONE).
Molecular Formula
- O3
Molecular Weight
- 47.997
Classification Codes
Classification Codes
- Air Pollutants
- Antiviral (COVID-19)
- Environmental Pollutants
- Human Data
- Mutation Data
- Noxae
- Oxidants
- Oxidants, Photochemical
- Reproductive Effect
- Skin / Eye Irritant
- Tumor Data
Superlist Classification Codes
- Threshold Planning Quantity (TPQ) = 100 lb
- TWA (0.05 ppm heavy work; 0.08 ppm moderate work; 0.10 ppm light work; 0.20 ppm heavy, moderate or light workloads (<2 hours)); Not classifiable as a human carcinogen
- TWA 0.1 ppm (0.2 mg/m3)
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Names and Synonyms
Name of Substance
- Ozone
MeSH Heading
- Ozone
Synonyms
- CCRIS 4503
- EINECS 233-069-2
- HSDB 717
- Oxygen, mol (O3)
- Ozon
- Ozon [Polish]
- Ozone
- Ozone heavy work
- Triatomic oxygen
- UNII-66H7ZZK23N
Systematic Name
- Ozone
Superlist Names
- Ozone
- Ozone heavy, moderate, or light workloads (<2 hours)
- Ozone light work
- Ozone moderate work
Registry Numbers
CAS Registry Number
- 10028-15-6
FDA UNII
- 66H7ZZK23N
Other Registry Numbers
- 412908-40-8
- 728855-47-8
- 74087-86-8
- 855426-80-1
System Generated Number
- 0010028156
Structure Descriptors
InChI
InChI=1S/O3/c1-3-2InChIKey
CBENFWSGALASAD-UHFFFAOYSA-NSmiles
[O-][O+]=OToxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LC50 | inhalation | 34500ppb/3H (34.5ppm) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Industrial Medicine and Surgery. Vol. 25, Pg. 301, 1956. |
guinea pig | LC50 | inhalation | 24800ppb/3H (24.8ppm) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Industrial Medicine and Surgery. Vol. 26, Pg. 63, 1957. |
hamster | LC50 | inhalation | 10500ppb/4H (10.5ppm) | AMA Archives of Industrial Health. Vol. 15, Pg. 181, 1957. | |
human | LCLo | inhalation | 50ppm/30M (50ppm) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION BEHAVIORAL: HEADACHE | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 446, 1969. |
human | TCLo | inhalation | 200ppb/4H/4D- (0.2ppm) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES CARDIAC: PULSE RATE | American Journal of Respiratory and Critical Care Medicine. Vol. 161, Pg. 1855, 2000. |
human | TCLo | inhalation | 600ppb/2H (0.6ppm) | LUNGS, THORAX, OR RESPIRATION: COUGH LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | American Review of Respiratory Disease. Vol. 118, Pg. 287, 1978. |
human | TCLo | inhalation | 1ppm (1ppm) | LUNGS, THORAX, OR RESPIRATION: COUGH LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Archives of Environmental Health. Vol. 10, Pg. 295, 1965. |
human | TCLo | inhalation | 100ppm/1M (100ppm) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" | News Edition, American Chemical Society. Vol. 19, Pg. 686, 1941. |
man | TCLo | inhalation | 80ppb/6.6H (0.08ppm) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: COUGH LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Archives of Environmental Health. Vol. 46, Pg. 145, 1991. |
man | TCLo | inhalation | 1860ppb/75M (1.86ppm) | LUNGS, THORAX, OR RESPIRATION: COUGH CARDIAC: PULSE RATE SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE | Archives of Environmental Health. Vol. 10, Pg. 517, 1965. |
mouse | LC50 | inhalation | 12600ppb/3H (12.6ppm) | BLOOD: HEMORRHAGE LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA | Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 16, Pg. 22, 1957. |
rabbit | LC50 | inhalation | 36ppm/3H (36ppm) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Industrial Medicine and Surgery. Vol. 25, Pg. 301, 1956. |
rat | LC50 | inhalation | 4800ppb/4H (4.8ppm) | LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA BLOOD: HEMORRHAGE | AMA Archives of Industrial Health. Vol. 15, Pg. 181, 1957. |
women | TCLo | inhalation | 350ppb/75M (0.35ppm) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Inhalation Toxicology. Vol. 12, Pg. 151, 2000. |