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Substance Name: Magnesium sulfate [USAN:JAN]
RN: 10034-99-8
UNII: SK47B8698T
InChIKey: WRUGWIBCXHJTDG-UHFFFAOYSA-L

Note

  • A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 1992, p1083)

Molecular Formulas

  • Mg-S-O4.7H2-O
  • O4-S.Mg.7H2-O

Molecular Weight

  • 246.4706
 

Classification Codes

  • Analgesics
  • Anesthetics
  • Anti-Arrhythmia Agents
  • Anticonvulsant
  • Anticonvulsants
  • Calcium Channel Blockers
  • Cardiovascular Agents
  • Central Nervous System Agents
  • Central Nervous System Depressants
  • Electrolyte Replenisher
  • Human Data
  • Laxative
  • Membrane Transport Modulators
  • Peripheral Nervous System Agents
  • Replenisher (Electrolyte)
  • Reproductive Control Agents
  • Sensory System Agents
  • Tocolytic Agents
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Names and Synonyms

Name of Substance

  • Magnesium sulfate [USAN:JAN]

MeSH Heading

  • Magnesium sulfate

Synonyms

  • Magnesium sulfate
  • Magnesium sulfate (1:1) heptahydrate
  • Magnesium sulfate heptahydrate
  • Magnesium sulfate heptahydrate (MgSO4.7H2O)
  • Sulfuric acid, magnesium salt (1:1), heptahydrate
  • UNII-SK47B8698T

Systematic Names

  • Magnesium(II), sulfate, heptahydrate
  • Sulfuric acid magnesium salt (1:1), heptahydrate

Superlist Name

  • Magnesium sulfate heptahydrate

Registry Numbers

CAS Registry Number

  • 10034-99-8

FDA UNII

  • SK47B8698T

Related Registry Number

  • 7487-88-9 (Parent)

System Generated Number

  • 0010034998

Molecular Formulas

Molecular Formulas

  • Mg-S-O4.7H2-O
  • O4-S.Mg.7H2-O

Molecular Formula Fragments

  • COMPONENT
  • H2-O
  • Mg
  • Mg-S-O4
  • O4-S

Structure Descriptors

InChI

1S/Mg.H2O4S.7H2O/c;1-5(2,3)4;;;;;;;/h;(H2,1,2,3,4);7*1H2/q+2;;;;;;;;/p-2

InChIKey

WRUGWIBCXHJTDG-UHFFFAOYSA-L

Smiles

O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[Mg+2]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TDLo oral 183mg/kg/4H-I (183mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" Journal of Toxicology, Clinical Toxicology. Vol. 20, Pg. 107, 1983.
women LDLo intraduodenal 5344mg/kg (5344mg/kg)   Archiv fuer Toxikologie. Vol. 27, Pg. 129, 1971.