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Substance Name: Boric acid [JAN:NF]
RN: 10043-35-3
UNII: R57ZHV85D4
InChIKey: KGBXLFKZBHKPEV-UHFFFAOYSA-N

Molecular Formulas

  • B-H3-O3
  • H3-B-O3

Molecular Weight

  • 61.8317
 

Classification Codes

  • Agricultural Chemical
  • Drug / Therapeutic Agent
  • Fungicide, Bactericide, Wood Preservative
  • Herbicide
  • Human Data
  • Insecticide
  • Insecticides
  • Mutation Data
  • Pesticides
  • Pharmaceutic Necessity
  • Reproductive Effect
  • Skin / Eye Irritant
  • Tumor Data

Names and Synonyms

Name of Substance

  • Boric acid
  • Boric acid [JAN:NF]
  • Orthoboric acid

Synonyms

  • AI3-02406
  • Basilit B
  • Boracic acid
  • Boric acid
  • Boric acid (BH3O3)
  • Boric acid (H3BO3)
  • Boric acid (VAN)
  • Borofax
  • Boron hydroxide
  • Boron trihydroxide
  • Borsaeure
  • Borsaure
  • Borsaure [German]
  • Caswell No. 109
  • CCRIS 855
  • component of Aci-Jel
  • Dr.'s 1 Flea Terminator DF
  • Dr.'s 1 Flea Terminator DFPBO
  • Dr.'s 1 Flea Terminator DT
  • Dr.'s 1 Flea Terminator DTPBO
  • EC 233-139-2
  • EINECS 233-139-2
  • EPA Pesticide Chemical Code 011001
  • Flea Prufe
  • HSDB 1432
  • NCI-C56417
  • Niban Granular Bait
  • NSC 81726
  • Optibor
  • Orthoboric acid
  • Orthoboric acid (B(OH)3)
  • Orthoborsaeure
  • Super Flea Eliminator
  • Three elephant
  • Trihydroxyborone
  • UNII-R57ZHV85D4

Systematic Names

  • Boric acid
  • Boric acid (H3BO3)
  • Boric acid, crude natural, containing not more than 85 per cent ofH3BO3 calculated on the dry weight

Superlist Names

  • Boric acid
  • Boric acid (H3BO3)

Mixture Names

  • Acidum boricum
  • Bluboro
  • Borofax
  • Collyrium Eye Wash
  • Collyrium Fresh-Eye Drops

Registry Numbers

CAS Registry Number

  • 10043-35-3

FDA UNII

  • R57ZHV85D4

Other Registry Numbers

  • 11113-50-1
  • 12795-04-9
  • 30698-98-7

Related Registry Numbers

  • 13460-50-9 (HBO2)
  • 13813-79-1 (H3(10)BO3)

System Generated Number

  • 0010043353

Structure Descriptors

InChI

1S/BH3O3/c2-1(3)4/h2-4H

InChIKey

KGBXLFKZBHKPEV-UHFFFAOYSA-N

Smiles

B(O)(O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
child LDLo skin 1500mg/kg (1500mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE
Quarterly Journal of Pharmacy & Pharmacology. Vol. 6, Pg. 714, 1933.
child LDLo skin 4gm/kg/4D (4000mg/kg)   Muenchener Medicinische Wochenschrift. Vol. 52, Pg. 763, 1905.
child TDLo oral 500mg/kg (500mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING Journal of Toxicology, Clinical Toxicology. Vol. 24, Pg. 269, 1986.
dog LDLo oral 1780mg/kg (1780mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

BRAIN AND COVERINGS: MENINGEAL CHANGES

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
JAMA, Journal of the American Medical Association. Vol. 128, Pg. 266, 1945.
dog LDLo parenteral 1gm/kg (1000mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) Rassegna di Terapia e Patologia Clinica. Vol. 1, Pg. 472, 1929.
dog LDLo subcutaneous 1gm/kg (1000mg/kg) BRAIN AND COVERINGS: MENINGEAL CHANGES

GASTROINTESTINAL: NAUSEA OR VOMITING

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
JAMA, Journal of the American Medical Association. Vol. 128, Pg. 266, 1945.
guinea pig LD50 subcutaneous 1200mg/kg (1200mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

BEHAVIORAL: TREMOR

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
U.S. Army, Chemical Corps Medical Division Special Report. Vol. #2, Pg. 1950,
guinea pig LDLo oral 1gm/kg (1000mg/kg) GASTROINTESTINAL: OTHER CHANGES

GASTROINTESTINAL: NAUSEA OR VOMITING
Revista de la Asociacion Medica Argentina. Vol. 46, Pg. 1493, 1932.
infant LDLo oral 934mg/kg (934mg/kg)   JAMA, Journal of the American Medical Association. Vol. 90, Pg. 382, 1928.
infant LDLo skin 1200mg/kg (1200mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
JAMA, Journal of the American Medical Association. Vol. 129, Pg. 332, 1945.
infant LDLo subcutaneous 1100mg/kg (1100mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BEHAVIORAL: TREMOR
U.S. Army, Chemical Corps Medical Division Special Report. Vol. #2, Pg. 1950,
infant TDLo oral 800mg/kg/4W-I (800mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Archives of Disease in Childhood. Vol. 58, Pg. 737, 1983.
man LDLo oral 429mg/kg (429mg/kg) CARDIAC: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"
Journal of Toxicology, Clinical Toxicology. Vol. 31, Pg. 345, 1993.
man LDLo skin 2430mg/kg (2430mg/kg) SKIN AND APPENDAGES (SKIN): PRIMARY IRRITATION: AFTER TOPICAL EXPOSURE

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
JAMA, Journal of the American Medical Association. Vol. 128, Pg. 266, 1945.
man LDLo unreported 147mg/kg (147mg/kg)   "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
man TDLo unreported 170mg/kg (170mg/kg) BEHAVIORAL: WAKEFULNESS

BEHAVIORAL: ANOREXIA (HUMAN

GASTROINTESTINAL: NAUSEA OR VOMITING
Rassegna di Terapia e Patologia Clinica. Vol. 1, Pg. 472, 1929.
mouse LD50 intravenous 1240mg/kg (1240mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Pharmacology and Experimental Therapeutics. Vol. 134, Pg. 117, 1961.
mouse LD50 oral 3450mg/kg (3450mg/kg)   JAMA, Journal of the American Medical Association. Vol. 128, Pg. 266, 1945.
mouse LD50 subcutaneous 1740mg/kg (1740mg/kg)   JAMA, Journal of the American Medical Association. Vol. 128, Pg. 266, 1945.
mouse LDLo intraperitoneal 800mg/kg (800mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ATAXIA
"Boron, Metallo-Boron Compounds and Boranes," Adams, R.M., ed., New York, John Wiley & Sons, Inc., 1964Vol. -, Pg. 693, 1964.
rabbit LDLo intravenous 800mg/kg (800mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
"Boron, Metallo-Boron Compounds and Boranes," Adams, R.M., ed., New York, John Wiley & Sons, Inc., 1964Vol. -, Pg. 693, 1964.
rabbit LDLo oral 4gm/kg (4000mg/kg) BEHAVIORAL: TREMOR

GASTROINTESTINAL: NAUSEA OR VOMITING

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
U.S. Army, Chemical Corps Medical Division Special Report. Vol. #2, Pg. 1950,
rabbit LDLo parenteral 670mg/kg (670mg/kg)   Rassegna di Terapia e Patologia Clinica. Vol. 1, Pg. 472, 1929.
rabbit LDLo subcutaneous 150mg/kg (150mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
rat LCLo inhalation 28mg/m3/4H (28mg/m3)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 27, 1982.
rat LD50 intravenous 1330mg/kg (1330mg/kg) BEHAVIORAL: TREMOR

GASTROINTESTINAL: NAUSEA OR VOMITING

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
U.S. Army, Chemical Corps Medical Division Special Report. Vol. #2, Pg. 1950,
rat LD50 oral 2660mg/kg (2660mg/kg)   JAMA, Journal of the American Medical Association. Vol. 128, Pg. 266, 1945.
rat LD50 subcutaneous 1400mg/kg (1400mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ATAXIA
"Boron, Metallo-Boron Compounds and Boranes," Adams, R.M., ed., New York, John Wiley & Sons, Inc., 1964Vol. -, Pg. 693, 1964.
women LDLo oral 200mg/kg (200mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BEHAVIORAL: FLUID INTAKE

GASTROINTESTINAL: NAUSEA OR VOMITING
Lancet. Vol. 2, Pg. 162, 1917.
women TDLo oral 400mg/kg (400mg/kg) GASTROINTESTINAL: OTHER CHANGES

GASTROINTESTINAL: NAUSEA OR VOMITING

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 32, Pg. 804, 1990.