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Substance Name: Cobicistat [USAN:INN]
RN: 1004316-88-4
UNII: LW2E03M5PG
InChIKey: ZCIGNRJZKPOIKD-CQXVEOKZSA-N
Note
- A carbamate and thiazole derivative that functions as a CYTOCHROME P450 CYP3A INHIBITOR to enhance the concentration of ANTI-HIV AGENTS, with which it is used in combination, for the treatment of HIV INFECTIONS.
Molecular Formula
- C40-H53-N7-O5-S2
Molecular Weight
- 776.0347
Classification Codes
- Anti-HIV Agents
- Anti-Infective Agents
- Anti-Retroviral Agents
- Antiviral (COVID-19)
- Antiviral Agents
- Cytochrome P-450 CYP3A Inhibitors
- Cytochrome P-450 Enzyme Inhibitors
- Enzyme Inhibitors
- Metabolic Side Effects of Drugs and Substances
- Treatment of HIV-1 Infection
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Names and Synonyms
Name of Substance
- Cobicistat
- Cobicistat [USAN:INN]
MeSH Heading
- Cobicistat
Synonyms
- Cobicistat
- GS 9350
- GS-9350
- Tybost
- UNII-LW2E03M5PG
Systematic Names
- 2,7,10,12-Tetraazatridecanoic acid, 12-methyl-13-(2-(1-methylethyl)-4-thiazolyl)-9-(2-(4-morpholinyl)ethyl)-8,11-dioxo-3,6-bis(phenylmethyl)-, 5-thiazolylmethyl ester, (3R,6R,9S)-
- Thiazol-5-ylmethyl ((1R,4R)-1-benzyl-4-({(2S)-2-((methyl{(2-(1-methylethyl)thiazol-4-yl)methyl}carbamoyl)amino)-4-(morpholin-4-yl)butanoyl}amino)-5-phenylpentyl)carbamate
Registry Numbers
CAS Registry Number
- 1004316-88-4
FDA UNII
- LW2E03M5PG
System Generated Number
- 1004316884