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Substance Name: Indolidan [USAN:INN:BAN]
RN: 100643-96-7
UNII: 0751ZOW7OR
InChIKey: LZCQFJKUAIWHRW-UHFFFAOYSA-N

Classification Codes

  • Cardiotonic
  • Drug / Therapeutic Agent

Molecular Formula

  • C14-H15-N3-O2

Molecular Weight

  • 257.292
 
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Names and Synonyms

Name of Substance

  • Indolidan
  • Indolidan [USAN:INN:BAN]

Synonyms

  • 1,3-Dihydro-3,3-dimethyl-5-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)-2H-indol-2-one
  • 3,3-Dimethyl-5-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)-2-indolinone
  • BRN 4874739
  • Indolidan
  • Indolidanum
  • Indolidanum [Latin]
  • LY 195115
  • UNII-0751ZOW7OR

Systematic Name

  • 2H-Indol-2-one, 1,3-dihydro-3,3-dimethyl-5-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)-

Registry Numbers

CAS Registry Number

  • 100643-96-7

FDA UNII

  • 0751ZOW7OR

System Generated Number

  • 0100643967

Structure Descriptors

InChI

1S/C14H15N3O2/c1-14(2)9-7-8(3-4-11(9)15-13(14)19)10-5-6-12(18)17-16-10/h3-4,7H,5-6H2,1-2H3,(H,15,19)(H,17,18)

InChIKey

LZCQFJKUAIWHRW-UHFFFAOYSA-N

Smiles

c12c(NC(C2(C)C)=O)ccc(c1)C=1CCC(=O)NN1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD oral > 10mg/kg (10mg/kg) CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP Toxicology Letters. Vol. 38, Pg. 177, 1987.
monkey LD oral > 5mg/kg (5mg/kg) CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP Toxicology Letters. Vol. 38, Pg. 177, 1987.
mouse LDLo oral 5gm/kg (5000mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BLOOD: HEMORRHAGE

BEHAVIORAL: MUSCLE WEAKNESS
Toxicology Letters. Vol. 38, Pg. 177, 1987.
rat LDLo oral 5gm/kg (5000mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: MUSCLE WEAKNESS

BLOOD: HEMORRHAGE
Toxicology Letters. Vol. 38, Pg. 177, 1987.