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Substance Name: Imipramine pamoate
RN: 10075-24-8
UNII: MC34P30298
InChIKey: BPQZYOJIXDMZSX-UHFFFAOYSA-N

Note

  • The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.

Molecular Formula

  • C23-H16-O6.2C19-H24-N2

Molecular Weight

  • 949.1986
 

Classification Codes

  • Adrenergic Uptake Inhibitors
  • Antidepressive Agents, Tricyclic

Names and Synonyms

Results Name

  • Imipramine pamoate

Name of Substance

  • Imipramine pamoate

Synonyms

  • 5H-Dibenz(b,f)azepine, 5-(3-(dimethylamino)propyl)-10,11-dihydro-, pamoate
  • EINECS 233-206-6
  • Imipramine pamoate
  • Tofranil-PM
  • UNII-MC34P30298

Systematic Names

  • 2-Naphthalenecarboxylic acid, 4,4'-methylenebis(3-hydroxy-, compd. with 10,11-dihydro-N,N-dimethyl-5H-dibenz(b,f)azepine-5-propanamine (1:2)
  • 4,4'-Methylenebis(3-hydroxy-2-naphthoic) acid, compound with 10,11-dihydro-N,N-dimethyl-5H-dibenz(b,f)azepine-5-propylamine (1:2)

Registry Numbers

CAS Registry Number

  • 10075-24-8

FDA UNII

  • MC34P30298

Other Registry Number

  • 22540-17-6

System Generated Number

  • 0010075248

Molecular Formulas

Molecular Formula

  • C23-H16-O6.2C19-H24-N2

Molecular Formula Fragments

  • C19-H24-N2
  • C23-H16-O6
  • COMPONENT

Structure Descriptors

InChI

1S/C23H16O6.2C19H24N2/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;2*1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2*3-6,8-11H,7,12-15H2,1-2H3

InChIKey

BPQZYOJIXDMZSX-UHFFFAOYSA-N

Smiles

CN(C)CCCN1c2ccccc2CCc3c1cccc3.CN(C)CCCN1c2ccccc2CCc3c1cccc3.c1ccc2c(c1)cc(c(c2Cc3c4ccccc4cc(c3O)C(=O)O)O)C(=O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 oral 7500mg/kg (7500mg/kg)   Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.