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Substance Name: Lorvotuzumab mertansine [USAN:INN]
RN: 1008106-64-6
UNII: 0IVD6ASY0W

Notes

  • A compound comprised of a CD56-targeted humanized N901 antibody conjugated to the company's proprietary cytotoxic agent. DM1, using its tumor-activated prodrug technology, for the potential treatment of cancers that express CD56, in particular, small-cell lung cancer.
  • Has antineoplastic activity.

Molecular Formula

  • Unspecified

Molecular Weight

  • 868.4844
 

Classification Codes

  • Antineoplastic Agents
  • Antineoplastic Agents, Immunological
  • Antineoplastic Agents, Phytogenic
  • Immunotoxins
  • Noxae
  • Oncology
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Links to Resources

Names and Synonyms

Name of Substance

  • Lorvotuzumab mertansine [USAN:INN]

Synonyms

  • BB 10901
  • BB-10901
  • huN 901DM1
  • huN901-DM1
  • IMGN 901
  • IMGN-901
  • IMGN901
  • Lorvotuzumab conjugated with mertansine
  • Lorvotuzumab mertansine
  • UNII-0IVD6ASY0W

Registry Numbers

CAS Registry Number

  • 1008106-64-6

FDA UNII

  • 0IVD6ASY0W

System Generated Number

  • 1008106646

Structure Descriptors

Smiles

[*]NC(=O)CCC(C)SSCCC(=O)N(C)[C@@H](C)C(=O)O[C@H]1CC(=O)N(C)c2cc(C\C(=C\C=C\[C@@H](OC)[C@@]3(O)C[C@H](OC(=O)N3)[C@@H](C)[C@@H]4O[C@@]14C)\C)cc(OC)c2Cl