Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Silmitasertib [INN]
RN: 1009820-21-6
UNII: C6RWP0N0L2
InChIKey: MUOKSQABCJCOPU-UHFFFAOYSA-N

Note

  • NCI: An orally bioavailable small-molecule inhibitor of CK2 with potential antineoplastic activity. Silmitasertib selectively binds to and inhibits the enzyme casein kinase II (CK2), which may lead to an inhibition of cellular proliferation. CK2, a protein kinase often overexpressed in a variety of cancer cell types, appears to be correlated with malignant transformation, tumor growth and survival. (NCI Thesaurus)

Molecular Weight

  • 349.7758
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Silmitasertib [INN]

Synonyms

  • CX 4945
  • CX-4945
  • CX4945
  • Silmitasertib
  • UNII-C6RWP0N0L2

Registry Numbers

CAS Registry Number

  • 1009820-21-6

FDA UNII

  • C6RWP0N0L2

System Generated Number

  • 1009820216

Structure Descriptors

InChI

1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)

InChIKey

MUOKSQABCJCOPU-UHFFFAOYSA-N

Smiles

OC(=O)c1ccc2c(c1)nc(Nc3cccc(Cl)c3)c4ccncc24