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Substance Name: Triphenyl phosphite
RN: 101-02-0
UNII: 9P45GRD24X
InChIKey: HVLLSGMXQDNUAL-UHFFFAOYSA-N

Classification Code

  • Skin / Eye Irritant

Molecular Formula

  • C18-H15-O3-P

Molecular Weight

  • 310.2875
 
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Names and Synonyms

Name of Substance

  • Triphenyl phosphite

Synonyms

  • 4-06-00-00695 (Beilstein Handbook Reference)
  • ADK Stab TPP
  • Advance TPP
  • AI3-07866
  • BRN 1079456
  • CCRIS 4890
  • EC 202-908-4
  • EFED
  • EINECS 202-908-4
  • HSDB 2571
  • JP 360
  • Mellite 310
  • NSC 43789
  • P 36
  • P 36 (stabilizer)
  • Phenyl phosphite
  • Phosclere T 36
  • Phosphorous acid, triphenyl ester
  • RTECS TD5824000
  • Stabilizer P 36
  • Sumilizer TPP-R
  • Sumilizer TTP-R
  • TP 1 (plasticizer)
  • TPP
  • TPP (plasticizer)
  • TPP (VAN)
  • Trifenoxyfosfin
  • Trifenoxyfosfin [Czech]
  • Trifenylfosfit
  • Trifenylfosfit [Czech]
  • Triphenoxyphosphine
  • Triphenyl phosphite
  • Tris(phenoxy)phosphine
  • UNII-9P45GRD24X
  • Weston TPP

Systematic Names

  • Phenyl phosphite ((C6H5O)3P) (6CI,7CI)
  • Phosphorous acid, triphenyl ester
  • Triphenyl phosphite

Superlist Names

  • Phosphorous acid, triphenyl ester
  • Triphenyl phosphite

Registry Numbers

CAS Registry Number

  • 101-02-0

FDA UNII

  • 9P45GRD24X

System Generated Number

  • 0000101020

Structure Descriptors

InChI

1S/C18H15O3P/c1-4-10-16(11-5-1)19-22(20-17-12-6-2-7-13-17)21-18-14-8-3-9-15-18/h1-15H

InChIKey

HVLLSGMXQDNUAL-UHFFFAOYSA-N

Smiles

c1ccc(cc1)OP(Oc2ccccc2)Oc3ccccc3

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo intraperitoneal 100mg/kg (100mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: TREMOR
National Technical Information Service. Vol. OTS0570901,
cat LDLo subcutaneous 300mg/kg (300mg/kg) BEHAVIORAL: ATAXIA Journal of Pharmacology and Experimental Therapeutics. Vol. 49, Pg. 78, 1933.
chicken LDLo intravenous 50mg/kg (50mg/kg) AUTONOMIC NERVOUS SYSTEM: GAGLION BLOCK Nippon Eiseigaku Zasshi. Japanese Journal of Hygiene. Vol. 44, Pg. 118, 1989.
chicken LDLo oral 250mg/kg (250mg/kg) BEHAVIORAL: ATAXIA National Technical Information Service. Vol. OTS0532280,
chicken LDLo subcutaneous 375mg/kg (375mg/kg) BEHAVIORAL: FOOD INTAKE (ANIMAL)

BEHAVIORAL: ATAXIA
National Technical Information Service. Vol. OTS0532280,
mammal (species unspecified) LD50 intraperitoneal 250mg/kg (250mg/kg) BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

CARDIAC: OTHER CHANGES
AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 5, Pg. 311, 1952.
mouse LD50 intraperitoneal 266mg/kg (266mg/kg)   Agricultural and Biological Chemistry. Vol. 31, Pg. 1288, 1967.
mouse LD50 oral 1080mg/kg (1080mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(12), Pg. 53, 1987.
mouse LD50 unreported 1360mg/kg (1360mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: TREMOR
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 21(9), Pg. 55, 1977.
rabbit LDLo skin 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) National Technical Information Service. Vol. OTS0532280,
rat LC inhalation > 6700mg/m3/1H (6700mg/m3)   National Technical Information Service. Vol. OTS0532280,
rat LD50 intraperitoneal 250mg/kg (250mg/kg)   "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 1117, 1986.
rat LD50 oral 444mg/kg (444mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 46(12), Pg. 13, 1981.
rat LD50 unreported 1490mg/kg (1490mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 21(9), Pg. 55, 1977.
rat LDLo subcutaneous 2gm/kg (2000mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: TREMOR

PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)
Journal of Pharmacology and Experimental Therapeutics. Vol. 49, Pg. 78, 1933.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 25 deg C   EXP
Boiling Point 360 deg C   EXP
log P (octanol-water) 6.620 (none)   EST
Atmospheric OH Rate Constant 1.08E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.