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Substance Name: Triphenyl phosphite
RN: 101-02-0
UNII: 9P45GRD24X
InChIKey: HVLLSGMXQDNUAL-UHFFFAOYSA-N

Classification Code

  • Skin / Eye Irritant

Molecular Formula

  • C18-H15-O3-P

Molecular Weight

  • 310.2875
 
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Names and Synonyms

Name of Substance

  • Triphenyl phosphite

Synonyms

  • 4-06-00-00695 (Beilstein Handbook Reference)
  • ADK Stab TPP
  • Advance TPP
  • AI3-07866
  • BRN 1079456
  • CCRIS 4890
  • EC 202-908-4
  • EFED
  • EINECS 202-908-4
  • HSDB 2571
  • JP 360
  • Mellite 310
  • NSC 43789
  • P 36
  • P 36 (stabilizer)
  • Phenyl phosphite
  • Phosclere T 36
  • Phosphorous acid, triphenyl ester
  • Stabilizer P 36
  • Sumilizer TPP-R
  • Sumilizer TTP-R
  • TP 1 (plasticizer)
  • TPP
  • TPP (plasticizer)
  • TPP (VAN)
  • Trifenoxyfosfin
  • Trifenoxyfosfin [Czech]
  • Trifenylfosfit
  • Trifenylfosfit [Czech]
  • Triphenoxyphosphine
  • Triphenyl phosphite
  • Tris(phenoxy)phosphine
  • UNII-9P45GRD24X
  • Weston TPP

Systematic Names

  • Phenyl phosphite ((C6H5O)3P) (6CI,7CI)
  • Phosphorous acid, triphenyl ester
  • Triphenyl phosphite

Superlist Names

  • Phosphorous acid, triphenyl ester
  • Triphenyl phosphite

Registry Numbers

CAS Registry Number

  • 101-02-0

FDA UNII

  • 9P45GRD24X

System Generated Number

  • 0000101020

Structure Descriptors

InChI

1S/C18H15O3P/c1-4-10-16(11-5-1)19-22(20-17-12-6-2-7-13-17)21-18-14-8-3-9-15-18/h1-15H

InChIKey

HVLLSGMXQDNUAL-UHFFFAOYSA-N

Smiles

c1ccc(cc1)OP(Oc2ccccc2)Oc3ccccc3

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo intraperitoneal 100mg/kg (100mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: TREMOR
National Technical Information Service. Vol. OTS0570901,
cat LDLo subcutaneous 300mg/kg (300mg/kg) BEHAVIORAL: ATAXIA Journal of Pharmacology and Experimental Therapeutics. Vol. 49, Pg. 78, 1933.
chicken LDLo intravenous 50mg/kg (50mg/kg) AUTONOMIC NERVOUS SYSTEM: GAGLION BLOCK Nippon Eiseigaku Zasshi. Japanese Journal of Hygiene. Vol. 44, Pg. 118, 1989.
chicken LDLo oral 250mg/kg (250mg/kg) BEHAVIORAL: ATAXIA National Technical Information Service. Vol. OTS0532280,
chicken LDLo subcutaneous 375mg/kg (375mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: FOOD INTAKE (ANIMAL)
National Technical Information Service. Vol. OTS0532280,
mammal (species unspecified) LD50 intraperitoneal 250mg/kg (250mg/kg) CARDIAC: OTHER CHANGES

BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 5, Pg. 311, 1952.
mouse LD50 intraperitoneal 266mg/kg (266mg/kg)   Agricultural and Biological Chemistry. Vol. 31, Pg. 1288, 1967.
mouse LD50 oral 1080mg/kg (1080mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(12), Pg. 53, 1987.
mouse LD50 unreported 1360mg/kg (1360mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: TREMOR
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 21(9), Pg. 55, 1977.
rabbit LDLo skin 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) National Technical Information Service. Vol. OTS0532280,
rat LC inhalation > 6700mg/m3/1H (6700mg/m3)   National Technical Information Service. Vol. OTS0532280,
rat LD50 intraperitoneal 250mg/kg (250mg/kg)   "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 1117, 1986.
rat LD50 oral 444mg/kg (444mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 46(12), Pg. 13, 1981.
rat LD50 unreported 1490mg/kg (1490mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 21(9), Pg. 55, 1977.
rat LDLo subcutaneous 2gm/kg (2000mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: TREMOR
Journal of Pharmacology and Experimental Therapeutics. Vol. 49, Pg. 78, 1933.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 25 deg C   EXP
Boiling Point 360 deg C   EXP
log P (octanol-water) 6.620 (none)   EST
Atmospheric OH Rate Constant 1.08E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.