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Substance Name: Bis(4-aminophenyl) ether
RN: 101-80-4
UNII: 28DLB4Z70T
InChIKey: HLBLWEWZXPIGSM-UHFFFAOYSA-N

Molecular Formula

  • C12-H12-N2-O

Molecular Weight

  • 200.24
 

Classification Codes

Classification Codes

  • Mutation Data
  • Tumor Data

Superlist Classification Codes

  • Overall Carcinogenic Evaluation: Group 2B
  • Reasonably Anticipated to be a Carcinogen

Names and Synonyms

Name of Substance

  • Bis(4-aminophenyl) ether
  • Di-(4-aminophenyl)ether

Synonyms

  • 4,4'-Diaminobiphenyl oxide
  • 4,4'-Diaminobiphenyloxide
  • 4,4'-Diaminodiphenyl ether
  • 4,4'-Diaminodiphenyl oxide
  • 4,4'-Diaminophenyl ether
  • 4,4'-Diaminophenyl oxide
  • 4,4'-Oxybisaniline
  • 4,4'-Oxybisbenzenamine
  • 4,4'-Oxydiphenylamine
  • 4,4-Diaminodiphenyl ether
  • 4,4-Oxydianiline
  • 4-13-00-01038 (Beilstein Handbook Reference)
  • 4-Aminophenyl ether
  • AI3-18375
  • Aniline, 4,4'-oxydi-
  • Bis(4-aminophenyl) ether
  • Bis(4-aminophenyl)ether
  • Bis(p-aminophenyl) ether
  • Bis(p-aminophenyl)ether
  • BRN 0475735
  • CCRIS 491
  • Dadpe
  • Diaminodiphenyl ether
  • EC 202-977-0
  • EINECS 202-977-0
  • Ether, 4,4'-diaminodiphenyl
  • HSDB 1316
  • NCI-C50146
  • NSC 37075
  • Oxybis(4-aminobenzene)
  • Oxydi-p-phenylenediamine
  • Oxydianiline
  • p,p'-Diaminodiphenyl ether
  • p,p'-Oxybis(aniline)
  • p,p'-Oxydianiline
  • p-Aminophenyl ether
  • UNII-28DLB4Z70T

Systematic Names

  • 4,4'-Oxydianiline
  • Aniline, 4,4'-oxydi-
  • Benzenamine, 4,4'-oxybis-

Superlist Names

  • 4,4'-Diaminodiphenyl ether
  • 4,4'-Oxydianiline
  • Aniline, 4,4'-oxydi-
  • Benzenamine, 4,4'-oxybis-
  • Diaminodiphenyl ether

Registry Numbers

CAS Registry Number

  • 101-80-4

FDA UNII

  • 28DLB4Z70T

Other Registry Numbers

  • 121509-79-3
  • 928208-61-1

System Generated Number

  • 0000101804

Structure Descriptors

InChI

1S/C12H12N2O/c13-9-1-5-11(6-2-9)15-12-7-3-10(14)4-8-12/h1-8H,13-14H2

InChIKey

HLBLWEWZXPIGSM-UHFFFAOYSA-N

Smiles

c1(Oc2ccc(N)cc2)ccc(N)cc1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 650mg/kg (650mg/kg)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 43, 1982.
mouse LD50 intraperitoneal 300mg/kg (300mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: MUSCLE WEAKNESS
Hygiene and Sanitation Vol. 33(10-12), Pg. 137, 1968.
mouse LD50 oral 685mg/kg (685mg/kg)   Hygiene and Sanitation Vol. 33(10-12), Pg. 137, 1968.
rabbit LD50 intraperitoneal 650mg/kg (650mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: MUSCLE WEAKNESS
Hygiene and Sanitation Vol. 33(10-12), Pg. 137, 1968.
rabbit LD50 oral 700mg/kg (700mg/kg)   Hygiene and Sanitation Vol. 33(10-12), Pg. 137, 1968.
rat LD50 intraperitoneal 365mg/kg (365mg/kg)   Hygiene and Sanitation Vol. 33(10-12), Pg. 137, 1968.
rat LD50 intraperitoneal 365mg/kg (365mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: MUSCLE WEAKNESS
Hygiene and Sanitation Vol. 33(10-12), Pg. 137, 1968.
rat LD50 oral 725mg/kg (725mg/kg)   Hygiene and Sanitation Vol. 33(10-12), Pg. 137, 1968.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 189 dec deg C   EXP
Boiling Point 350 deg C   EXP
log P (octanol-water) 1.36 (none)   EXP
Water Solubility 560 mg/L 25 EST
Vapor Pressure 4.36E-06 mm Hg 25 EST
Henry's Law Constant 1.50E-11 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 2.10E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.