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Substance Name: Sodium thiosulfate [USP:JAN]
RN: 10102-17-7
UNII: HX1032V43M
InChIKey: PODWXQQNRWNDGD-UHFFFAOYSA-L

Molecular Formulas

  • Na2-S2-O3.5H2-O
  • O3-S2.2Na.5H2-O

Molecular Weight

  • 248.183
 

Classification Codes

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antidote (to Cyanide Poisoning)
  • Antidotes
  • Antioxidants
  • Antitubercular Agents
  • Chelating Agents
  • Drug / Therapeutic Agent
  • Human Data
  • Protective Agents
  • Sequestering Agents
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Names and Synonyms

Name of Substance

  • Sodium thiosulfate
  • Sodium thiosulfate [USP:JAN]

Synonyms

  • Ametox
  • CCRIS 3952
  • Disodium thiosulfate pentahydrate
  • NSC-45624
  • Sodium thiosulfate
  • Sodium thiosulfate pentahydrate
  • Sulfactol
  • Thiosulfuric acid (H2S2O3), disodium salt, pentahydrate
  • UNII-HX1032V43M

Systematic Names

  • Sodium thiosulfate, pentahydrate
  • Thiosulfuric acid (H2S2O3), disodium salt, pentahydrate
  • Thiosulfuric acid, disodium salt, pentahydrate

Superlist Names

  • Sodium hyposulfite
  • Sodium thiosulfate
  • Sodium thiosulfate pentahydrate

Mixture Name

  • Tinver

Registry Numbers

CAS Registry Number

  • 10102-17-7

FDA UNII

  • HX1032V43M

Related Registry Number

  • 7772-98-7 (Parent)

System Generated Number

  • 0010102177

Molecular Formulas

Molecular Formulas

  • Na2-S2-O3.5H2-O
  • O3-S2.2Na.5H2-O

Molecular Formula Fragments

  • COMPONENT
  • H2-O
  • Na
  • Na2-S2-O3
  • O3-S2

Structure Descriptors

InChI

1S/2Na.H2O3S2.5H2O/c;;1-5(2,3)4;;;;;/h;;(H2,1,2,3,4);5*1H2/q2*+1;;;;;;/p-2

InChIKey

PODWXQQNRWNDGD-UHFFFAOYSA-L

Smiles

O.O.O.O.O.[Na+].[Na+].[O-]S(=O)(=O)[S-]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 3gm/kg (3000mg/kg) CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP

VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Cancer Chemotherapy Reports. Vol. 50, Pg. 255, 1966.
human TDLo oral 300mg/kg/7D (300mg/kg) LUNGS, THORAX, OR RESPIRATION: CYANOSIS Tohoku Journal of Experimental Medicine. Vol. 63, Pg. 383, 1956.
mouse LD50 intraperitoneal 5600mg/kg (5600mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 1713, 1981.
mouse LD50 intravenous 2350mg/kg (2350mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA
Kiso to Rinsho. Clinical Report. Vol. 13, Pg. 89, 1979.
rat LD50 intravenous > 2500mg/kg (2500mg/kg)   Yakkyoku. Pharmacy. Vol. 31, Pg. 959, 1980.