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Substance Name: Triacetin [USP:INN:BAN]
RN: 102-76-1
UNII: XHX3C3X673
InChIKey: URAYPUMNDPQOKB-UHFFFAOYSA-N
Note
- A triglyceride that is used as an antifungal agent.
Molecular Formula
- C9-H14-O6
Molecular Weight
- 218.204
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Anti-Infective Agents
- Antifungal
- Antifungal Agents
- Drug / Therapeutic Agent
- Skin / Eye Irritant
- Solvents
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Names and Synonyms
Name of Substance
- 1,2,3-Propanetriol triacetate
- Acetic, 1,2,3-propanetriyl ester
- Triacetin
- Triacetin [USP:INN:BAN]
MeSH Heading
- Triacetin
Synonyms
- 1,2,3-Propanetriol triacetate
- 1,2,3-Propanetriyl triacetate
- 4-02-00-00253 (Beilstein Handbook Reference)
- Acetin, tri-
- AI3-00661
- BRN 1792353
- CCRIS 9355
- EC 203-051-9
- EINECS 203-051-9
- Enzactin
- FEMA No. 2007
- FEMA Number 2007
- Fungacetin
- Glycerin triacetate
- Glycerol triacetate
- Glyceryl triacetate
- Glyped
- HSDB 585
- Kesscoflex TRA
- Kodaflex triacetin
- NSC 4796
- Triacetin
- Triacetina
- Triacetina [INN-Spanish]
- Triacetine
- Triacetine [INN-French]
- Triacetinum
- Triacetinum [INN-Latin]
- Triacetyl glycerine
- Triacetylglycerol
- UNII-XHX3C3X673
- Vanay
Systematic Names
- 1,2,3-Propanetriol, 1,2,3-triacetate
- 1,2,3-Propanetriol, triacetate
- Acetin, tri-
- Triacetin
Superlist Names
- 1,2,3-Propanetriol triacetate
- Acetin, tri-
- Glyceryl triacetate
- Triacetin
Registry Numbers
CAS Registry Number
- 102-76-1
FDA UNII
- XHX3C3X673
Other Registry Number
- 2102168-03-4
System Generated Number
- 0000102761
Structure Descriptors
InChI
1S/C9H14O6/c1-6(10)13-4-9(15-8(3)12)5-14-7(2)11/h9H,4-5H2,1-3H3InChIKey
URAYPUMNDPQOKB-UHFFFAOYSA-NSmiles
C(COC(C)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD50 | intravenous | 1500mg/kg (1500mg/kg) | Food and Cosmetics Toxicology. Vol. 16, Pg. 879, 1978. | |
| frog | LDLo | oral | 150mg/kg (150mg/kg) | Food and Cosmetics Toxicology. Vol. 16, Pg. 879, 1978. | |
| guinea pig | LDLo | intramuscular | 1740mg/kg (1740mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Journal of Pharmacology and Experimental Therapeutics. Vol. 76, Pg. 189, 1942. |
| mouse | LD50 | intraperitoneal | 1400mg/kg (1400mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: STIFFNESS PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE | Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 22, Pg. 368, 1963. |
| mouse | LD50 | intravenous | 1600mg/kg (1600mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Acta Physiologica Scandinavica. Vol. 40, Pg. 338, 1957. |
| mouse | LD50 | oral | 1100mg/kg (1100mg/kg) | PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: STIFFNESS | Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 22, Pg. 368, 1963. |
| mouse | LD50 | subcutaneous | 2300mg/kg (2300mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Proceedings of the Society for Experimental Biology and Medicine. Vol. 46, Pg. 26, 1941. |
| rabbit | LD50 | intravenous | 750mg/kg (750mg/kg) | Food and Cosmetics Toxicology. Vol. 16, Pg. 879, 1978. | |
| rat | LD50 | intraperitoneal | 2100mg/kg (2100mg/kg) | Food and Cosmetics Toxicology. Vol. 16, Pg. 879, 1978. | |
| rat | LD50 | oral | 3gm/kg (3000mg/kg) | AMA Archives of Industrial Health. Vol. 21, Pg. 28, 1960. | |
| rat | LD50 | subcutaneous | 2800mg/kg (2800mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Proceedings of the Society for Experimental Biology and Medicine. Vol. 46, Pg. 26, 1941. |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| Melting Point | 78 | deg C | EXP | |
| Boiling Point | 259 | deg C | EXP | |
| log P (octanol-water) | 0.25 | (none) | EXP | |
| Water Solubility | 5.80E+04 | mg/L | 25 | EXP |
| Vapor Pressure | 0.00248 | mm Hg | 25 | EXP |
| Henry's Law Constant | 1.23E-08 | atm-m3/mole | 25 | EST |
| Atmospheric OH Rate Constant | 7.81E-12 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.