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Substance Name: Sodium aurotiosulfate [INN]
RN: 10210-36-3
InChIKey: FJCMCHNDCIYVST-UHFFFAOYSA-J

Classification Codes

  • Antirheumatic
  • Drug / Therapeutic Agent
  • Human Data

Molecular Formula

  • O6-S4.Au.3Na.2H2-O

Molecular Weight

  • 490.198
 
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Names and Synonyms

Name of Substance

  • Sodium aurotiosulfate [INN]

Synonyms

  • Auricidine
  • Aurocidin
  • Aurolin
  • Auropex
  • Auropin
  • Aurosan
  • Aurothion
  • Aurotiosulfate de sodium
  • Aurotiosulfate de sodium [INN-French]
  • Aurotiosulfato sodico
  • Aurotiosulfato sodico [DCIT]
  • Crisalbine
  • Natrii aurotiosulfas
  • Natrii aurotiosulfas [INN-Latin]
  • Natrium-bis(thiosulfato)aurat(I)
  • Novacrysin
  • Sanochrysine
  • Sodium aurothiosulphate dihydrate
  • Sodium aurotiosulfate
  • Solfocrisol
  • Thiochrysine
  • Thiosulfuric acid, gold(1+) sodium salt(2:1:3), dihydrate

Systematic Name

  • Gold sodium thiosulfate, dihydrate

Registry Numbers

CAS Registry Number

  • 10210-36-3

System Generated Number

  • 0010210363

Molecular Formulas

Molecular Formula

  • O6-S4.Au.3Na.2H2-O

Molecular Formula Fragments

  • Au
  • COMPONENT
  • H2-O
  • Na
  • O6-S4

Structure Descriptors

InChI

1S/Au.3Na.2H2O3S2/c;;;;2*1-5(2,3)4/h;;;;2*(H2,1,2,3,4)/q4*+1;;/p-4

InChIKey

FJCMCHNDCIYVST-UHFFFAOYSA-J

Smiles

S(S(=O)(=O)[O-])[Au-]SS(=O)(=O)[O-].[Na+].[Na+].[Na+]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
human TDLo intramuscular 400ug/kg/1W (0.4mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, IRRITATIVE: AFTER SYSTEMIC EXPOSURE"

BLOOD: GRANULOCYTOPENIA

BLOOD: THROMBOCYTOPENIA
Annals of Internal Medicine. Vol. 37, Pg. 323, 1952.
mouse LD50 intraperitoneal 110mg/kg (110mg/kg)   Journal of Rheumatology. Vol. 12, Pg. 274, 1985.
mouse LDLo intravenous 100mg/kg (100mg/kg)   Experimental Medicine and Surgery. Vol. 3, Pg. 146, 1945.
mouse LDLo subcutaneous 400mg/kg (400mg/kg)   Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 57, Pg. 77, 1927.
rat LDLo intramuscular 35mg/kg (35mg/kg)   Proceedings of the Society for Experimental Biology and Medicine. Vol. 49, Pg. 121, 1942.