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Substance Name: Pyrimidine, 2-amino-4-(2-dibutylaminoethoxy)-
RN: 102207-73-8
InChIKey: QOKOFSWPBFMPCP-UHFFFAOYSA-N
Classification Code
- Drug / Therapeutic Agent
Molecular Formula
- C14-H26-N4-O
Molecular Weight
- 266.3864
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Names and Synonyms
Synonyms
- 2-Amino-4-(2-dibutylaminoethoxy)pyrimidine
- 2-Amino-4-dibutylaminoethoxypyrimidine
- 4-25-00-03351 (Beilstein Handbook Reference)
- BRN 0214494
- OR-1550
Systematic Name
- Pyrimidine, 2-amino-4-(2-dibutylaminoethoxy)-
Registry Numbers
CAS Registry Number
- 102207-73-8
System Generated Number
- 0102207738
Structure Descriptors
InChI
1S/C14H26N4O/c1-3-5-9-18(10-6-4-2)11-12-19-13-7-8-16-14(15)17-13/h7-8H,3-6,9-12H2,1-2H3,(H2,15,16,17)InChIKey
QOKOFSWPBFMPCP-UHFFFAOYSA-NSmiles
c1(nc(ccn1)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD50 | intravenous | 35mg/kg (35mg/kg) | GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 50, 1956. |
| dog | LD50 | oral | 450mg/kg (450mg/kg) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 50, 1956. |
| mouse | LD50 | intraperitoneal | 157mg/kg (157mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 50, 1956. |
| mouse | LD50 | intravenous | 44mg/kg (44mg/kg) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 50, 1956. |
| rabbit | LD50 | intravenous | 46mg/kg (46mg/kg) | GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 50, 1956. |
| rabbit | LD50 | oral | 1260mg/kg (1260mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 50, 1956. |
| rat | LD50 | intraperitoneal | 75mg/kg (75mg/kg) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 50, 1956. |
| rat | LD50 | oral | 1gm/kg (1000mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 50, 1956. |