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Substance Name: Pyrimidine, 2-amino-4-(2-diethylaminoethoxy)-
RN: 102207-75-0
InChIKey: WGNULDMOVQJCAF-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C10-H18-N4-O

Molecular Weight

  • 210.2792
 
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Names and Synonyms

Synonyms

  • 2-Amino-4-(2-diethylaminoethoxy)pyrimidine
  • 2-Amino-4-diethylaminoethoxypyrimidine
  • OR-1556

Systematic Name

  • Pyrimidine, 2-amino-4-(2-diethylaminoethoxy)-

Registry Numbers

CAS Registry Number

  • 102207-75-0

System Generated Number

  • 0102207750

Structure Descriptors

InChI

1S/C10H18N4O/c1-3-14(4-2)7-8-15-9-5-6-12-10(11)13-9/h5-6H,3-4,7-8H2,1-2H3,(H2,11,12,13)

InChIKey

WGNULDMOVQJCAF-UHFFFAOYSA-N

Smiles

c1(nc(ccn1)OCCN(CC)CC)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 165mg/kg (165mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 50, 1956.
dog LD50 oral 2750mg/kg (2750mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 50, 1956.
mouse LD50 intraperitoneal 252mg/kg (252mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 50, 1956.
mouse LD50 intravenous 174mg/kg (174mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 50, 1956.
rabbit LD50 intravenous 174mg/kg (174mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 50, 1956.
rabbit LD50 oral 875mg/kg (875mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 50, 1956.
rat LD50 intraperitoneal 75mg/kg (75mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 50, 1956.
rat LD50 oral 2gm/kg (2000mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 50, 1956.