Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Otenzepad [INN]
RN: 102394-31-0
UNII: OM7J0XAL0S
InChIKey: UBRKDAVQCKZSPO-UHFFFAOYSA-N

Note

  • Cardioselective muscarinic receptor antagonist.

Molecular Formula

  • C24-H31-N5-O2

Molecular Weight

  • 421.5419
 

Classification Codes

  • Anti-Arrhythmia Agents
  • Autonomic Agents
  • Cardiovascular Agents
  • Drug / Therapeutic Agent
  • Parasympatholytics
  • Peripheral Nervous System Agents
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Results Name

  • Otenzepad [INN]

Name of Substance

  • Otenzepad

Synonyms

  • AF-DX 116
  • AF-DX-116
  • BRN 4212983
  • Otenzepad
  • RTECS VC7966000
  • UNII-OM7J0XAL0S

Systematic Names

  • 6H-Pyrido(2,3-b)(1,4)benzodiazepin-6-one, 11-((2-((diethylamino)methyl)-1-piperidinyl)acetyl)-5,11-dihydro-
  • 6H-Pyrido(2,3-b)(1,4)benzodiazepin-6-one, 5,11-dihydro-11-((2-((diethylamino)methyl)-7-piperidinyl)acetyl)-

Registry Numbers

CAS Registry Number

  • 102394-31-0

FDA UNII

  • OM7J0XAL0S

Other Registry Number

  • 100158-38-1

System Generated Number

  • 0102394310

Structure Descriptors

InChI

1S/C24H31N5O2/c1-3-27(4-2)16-18-10-7-8-15-28(18)17-22(30)29-21-13-6-5-11-19(21)24(31)26-20-12-9-14-25-23(20)29/h5-6,9,11-14,18H,3-4,7-8,10,15-17H2,1-2H3,(H,26,31)

InChIKey

UBRKDAVQCKZSPO-UHFFFAOYSA-N

Smiles

CCN(CC)CC1CCCCN1CC(=O)N2c3ccccc3C(=O)Nc4c2nccc4

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 50mg/kg (50mg/kg)   Cardiovascular Drug Reviews. Vol. 9, Pg. 30, 1991.
mouse LD50 oral 600mg/kg (600mg/kg)   Cardiovascular Drug Reviews. Vol. 9, Pg. 30, 1991.
rat LD50 intravenous 83mg/kg (83mg/kg)   Cardiovascular Drug Reviews. Vol. 9, Pg. 30, 1991.
rat LD50 oral 1533mg/kg (1533mg/kg)   Cardiovascular Drug Reviews. Vol. 9, Pg. 30, 1991.