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Substance Name: Hydroxyzine pamoate [USP:JAN]
RN: 10246-75-0
UNII: M20215MUFR
InChIKey: ASDOKGIIKXGMNB-UHFFFAOYSA-N

Note

  • A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.

Molecular Formulas

  • C21-H27-Cl-N2-O2.C23-H16-O6
  • C23-H16-O6.C21-H27-Cl-N2-O2

Molecular Weight

  • 763.2827
 

Classification Code

  • Tranquilizer (Minor)
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Names and Synonyms

Name of Substance

  • Hydroxyzine pamoate [USP:JAN]

Synonyms

  • (+-)-2-(2-(4-(p-Chloro-alpha-phenylbenzyl)-1-piperazinyl)ethoxy)ethanol 4,4'-methylenebis(3-hydroxy-2-naphthoate) (1:1)
  • 2-(2-(4-(p-Chloro-alpha-phenylbenzyl)-1-piperazinyl)ethoxy)ethanol 4,4'-methylenebis(3-hydroxy-2-naphthoate) (1:1)
  • Atarax P
  • Bobsule
  • EINECS 233-582-1
  • Equipose
  • Ethanol, 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-, (+-)-, compd. with 4,4'-methylenebis(3-hydroxy-2-naphthalenecarboxylic acid) (1:1)
  • Hy-Pam
  • Hydroxyzine pamoate
  • Hydroxyzyne pamoate
  • Masmoran
  • Paxisitil
  • Paxistil
  • UNII-M20215MUFR
  • Vistaril
  • Vistaril Pamoate

Systematic Names

  • Ethanol, 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-, compd. with 4,4'-methylenebis(3-hydroxy-2-naphthalenecarboxylic acid) (1:1)
  • Hydroxyzine embonate

Registry Numbers

CAS Registry Number

  • 10246-75-0

FDA UNII

  • M20215MUFR

Related Registry Number

  • 68-88-2 (Parent)

System Generated Number

  • 0010246750

Molecular Formulas

Molecular Formulas

  • C21-H27-Cl-N2-O2.C23-H16-O6
  • C23-H16-O6.C21-H27-Cl-N2-O2

Molecular Formula Fragments

  • C21-H27-Cl-N2-O2
  • C23-H16-O6
  • COMPONENT

Structure Descriptors

InChI

1S/C23H16O6.C21H27ClN2O2/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25/h1-10,24-25H,11H2,(H,26,27)(H,28,29);1-9,21,25H,10-17H2

InChIKey

ASDOKGIIKXGMNB-UHFFFAOYSA-N

Smiles

c1ccc(cc1)C(c2ccc(cc2)Cl)N3CCN(CC3)CCOCCO.c1ccc2c(c1)cc(c(c2Cc3c4ccccc4cc(c3O)C(=O)O)O)C(=O)O