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Substance Name: Methamidophos [ANSI:BSI:ISO]
RN: 10265-92-6
UNII: 8Z083FM94W
InChIKey: NNKVPIKMPCQWCG-UHFFFAOYSA-N

Molecular Formula

  • C2-H8-N-O2-P-S

Molecular Weight

  • 141.1302
 

Classification Codes

Classification Codes

  • Acaricide
  • Agricultural Chemical
  • Avicide
  • Human Data
  • Insecticide
  • Insecticides
  • Mutation Data
  • Pesticides
  • Reproductive Effect

Superlist Classification Code

  • Threshold Planning Quantity (TPQ) = 100/10000 lb
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Names and Synonyms

Results Name

  • Methamidophos [ANSI:BSI:ISO]

Name of Substance

  • Methamidophos
  • Methamidophos [ANSI:BSI:ISO]

Synonyms

  • Acephate-met
  • AI3-27396
  • Amidor
  • Bayer 5546
  • BRN 1098870
  • Caswell No. 378A
  • CCRIS 9422
  • Chevron 9006
  • Chevron ortho 9006
  • CKB 1220
  • EINECS 233-606-0
  • ENT 27,396
  • EPA Pesticide Chemical Code 101201
  • Filitox
  • Hamidop
  • HSDB 1593
  • Metamidofos estrella
  • Metamidophos
  • Methamidophos
  • Methyl phosphoramidothioate ((MeO)(MeS)P(O)(NH2))
  • Monitor
  • Monitor (insecticide)
  • MTD
  • NSC 190987
  • O,S-Dimethyl phosphoramidothioate
  • Ortho 9006
  • Ortho Monitor
  • Patrole
  • Pillaron
  • RE 9006
  • Sniper
  • SRA 5172
  • Tahmabon
  • Tamanox
  • Tamaron
  • Thiophosphorsaeure-O,S-dimethylesteramid
  • Thiophosphorsaeure-O,S-dimethylesteramid [German]
  • UNII-8Z083FM94W

Systematic Names

  • Methamidophos
  • Phosphoramidothioic acid, O,S-dimethyl ester

Superlist Names

  • Methamidophos
  • Phosphoramidothioic acid, O,S-dimethyl ester

Registry Numbers

CAS Registry Number

  • 10265-92-6

FDA UNII

  • 8Z083FM94W

Other Registry Number

  • 115182-35-9

System Generated Number

  • 0010265926

Structure Descriptors

InChI

1S/C2H8NO2PS/c1-5-6(3,4)7-2/h1-2H3,(H2,3,4)

InChIKey

NNKVPIKMPCQWCG-UHFFFAOYSA-N

Smiles

P(=O)(OC)(SC)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - domestic LD50 oral 8mg/kg (8mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: ATAXIA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Archives of Environmental Contamination and Toxicology. Vol. 10, Pg. 185, 1981.
chicken LD50 oral 25mg/kg (25mg/kg)   "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 149, 1976.
guinea pig LD50 oral 30mg/kg (30mg/kg)   "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 149, 1976.
guinea pig LDLo subcutaneous 10mg/kg (10mg/kg)   Journal of Economic Entomology. Vol. 62, Pg. 934, 1969.
man TDLo oral 1429uL/kg (1.429mL/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

BEHAVIORAL: GENERAL ANESTHETIC

BEHAVIORAL: MUSCLE WEAKNESS
Archives of Toxicology. Vol. 73, Pg. 296, 1999.
man TDLo oral 257mg/kg (257mg/kg) PERIPHERAL NERVE AND SENSATION: FASCICULATIONS

SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE

SKIN AND APPENDAGES (SKIN): SWEATING: OTHER
New England Journal of Medicine. Vol. 306, Pg. 125, 1982.
man TDLo oral 600mg/kg (600mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

AUTONOMIC NERVOUS SYSTEM: PARASYMPATHOLYTIC

BEHAVIORAL: COMA
Toxicologist. Vol. 14, Pg. 390, 1994.
mouse LD50 intraperitoneal 5300ug/kg (5.3mg/kg)   Pesticide Biochemistry and Physiology. Vol. 7, Pg. 83, 1977.
mouse LD50 oral 14mg/kg (14mg/kg)   Pesticide Biochemistry and Physiology. Vol. 7, Pg. 83, 1977.
mouse LD50 unreported 27mg/kg (27mg/kg)   Journal of Agricultural and Food Chemistry. Vol. 18, Pg. 189, 1970.
quail LD50 oral 57500ug/kg (57.5mg/kg)   Pesticide Manual. Vol. 9, Pg. 563, 1991.
rabbit LD50 oral 10mg/kg (10mg/kg)   "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 149, 1976.
rabbit LD50 skin 118mg/kg (118mg/kg)   Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 333, 1973.
rat LC50 inhalation 162mg/m3/4H (162mg/m3)   "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc of Chemistry, 1983-86Vol. A265, Pg. 1984,
rat LD50 intraperitoneal 15mg/kg (15mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Pesticide Biochemistry and Physiology. Vol. 13, Pg. 267, 1980.
rat LD50 intravenous 10mg/kg (10mg/kg) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: TREMOR
Pesticide Biochemistry and Physiology. Vol. 18, Pg. 28, 1982.
rat LD50 oral 7500ug/kg (7.5mg/kg)   Agricultural Research Service, USDA Information Memorandum. Vol. 20, Pg. 7, 1966.
rat LD50 skin 50mg/kg (50mg/kg)   "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 149, 1976.
women TDLo oral 360mg/kg (360mg/kg) SKIN AND APPENDAGES (SKIN): SWEATING: OTHER

PERIPHERAL NERVE AND SENSATION: FASCICULATIONS

SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE
New England Journal of Medicine. Vol. 306, Pg. 125, 1982.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 46 deg C   EXP
log P (octanol-water) -0.8 (none)   EXP
Water Solubility 1.00E+06 mg/L 20 EXP
Vapor Pressure 3.53E-05 mm Hg 25 EXP
Henry's Law Constant 8.68E-10 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 2.78E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.