|
|
Substance Name: Chlorambucil sodium salt
RN: 1030-06-4
InChIKey: MXPCUEIEUDJYAC-UHFFFAOYSA-M
Note
- A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Molecular Formula
- C14-H18-Cl2-N-O2.Na
Molecular Weight
- 326.197
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Formulas
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Mutation Data
- Reproductive Effect
* denotes mobile formatted website
Links to Resources
NLM Resources (File Locators)
Other Resources (Internet Locators)
Search for this InChIKey on the Web
Names and Synonyms
Results Name
- Chlorambucil sodium salt
Synonyms
- CB 1348 sodium salt
- Chlorambucil sodium salt
- p-(Di-2-chloroethylamine)-phenyl butyric acid sodium salt
- p-N,N-Bis(2-chloroethyl)aminophenylbutyric acid sodium salt
- Sodium chlorambucil
Systematic Names
- Benzenebutanoic acid, 4-(bis(2-chloroethyl)amino)-, sodium salt (9CI)
- Butyric acid, 4-(p-(bis(2-chloroethyl)amino)phenyl)-, sodium salt
Registry Numbers
CAS Registry Number
- 1030-06-4
System Generated Number
- 0001030064
Molecular Formulas
Molecular Formula
- C14-H18-Cl2-N-O2.Na
Molecular Formula Fragments
- C14-H18-Cl2-N-O2
- COMPONENT
- Na
Structure Descriptors
InChI
1S/C14H19Cl2NO2.Na/c15-8-10-17(11-9-16)13-6-4-12(5-7-13)2-1-3-14(18)19;/h4-7H,1-3,8-11H2,(H,18,19);/q;+1/p-1InChIKey
MXPCUEIEUDJYAC-UHFFFAOYSA-MSmiles
c1(N(CCCl)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | unreported | 45mg/kg (45mg/kg) | British Journal of Pharmacology and Chemotherapy. Vol. 11, Pg. 437, 1956. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
log P (octanol-water) | 0.93 | (none) | EXP |
Physical property data is provided to ChemIDplus by SRC, Inc.