Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Morpholino-thalidomide
RN: 10329-95-0
InChIKey: IMFASZSXAQHCHV-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C18-H19-N3-O5

Molecular Weight

  • 357.364
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Results Name

  • Morpholino-thalidomide

Synonyms

  • 1-Methyl-morpholino-3-phthalimido-glutarimide
  • 1-Morpholinomethylthalidomide
  • BRN 1230262
  • CG 601
  • E-298
  • Morpholino-thalidomide
  • N-(1-(Morpholinomethyl)-2,6-dioxo-3-piperidyl)phthalimide
  • RTECS TE6580000

Systematic Names

  • 1H-Isoindole-1,3(2H)-dione, 2-(1-(4-morpholinylmethyl)-2,6-dioxo-3-piperidinyl)- (9CI)
  • Phthalimide, N-(1-(morpholinomethyl)-2,6-dioxo-3-piperidyl)-

Registry Numbers

CAS Registry Number

  • 10329-95-0

System Generated Number

  • 0010329950

Structure Descriptors

InChI

1S/C18H19N3O5/c22-15-6-5-14(18(25)20(15)11-19-7-9-26-10-8-19)21-16(23)12-3-1-2-4-13(12)17(21)24/h1-4,14H,5-11H2

InChIKey

IMFASZSXAQHCHV-UHFFFAOYSA-N

Smiles

C1(N(C(c2ccccc12)=O)[C@@H]1C(N(C(CC1)=O)CN1CCOCC1)=O)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 840mg/kg (840mg/kg) ENDOCRINE: CHANGE IN LH

ENDOCRINE: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 194, Pg. 39, 1971.
mouse LD50 oral 3gm/kg (3000mg/kg) ENDOCRINE: CHANGE IN LH

ENDOCRINE: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 194, Pg. 39, 1971.
rat LD50 intraperitoneal 1300mg/kg (1300mg/kg) ENDOCRINE: CHANGE IN LH

ENDOCRINE: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 194, Pg. 39, 1971.
rat LD50 oral > 8gm/kg (8000mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 194, Pg. 39, 1971.