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Substance Name: Morpholino-beta-thalidomide
RN: 10329-96-1
InChIKey: FDOBAWPDCWCNRJ-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C18-H19-N3-O5

Molecular Weight

  • 357.364
 
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Names and Synonyms

Results Name

  • Morpholino-beta-thalidomide

Name of Substance

  • CG 603

Synonyms

  • 1-Methyl-morpholino-4-phthalimido-glutarimide
  • BRN 1170135
  • CG 603
  • E-352
  • Morpholino-beta-thalidomide
  • N-(1-(Morpholinomethyl)-2,6-dioxo-4-piperidyl)phthalimide

Systematic Names

  • 1H-Isoindole-1,3(2H)-dione, 2-(1-(4-morpholinylmethyl)-2,6-dioxo-4-piperidinyl)- (9CI)
  • Phthalimide, N-(1-(morpholinomethyl)-2,6-dioxo-4-piperidyl)-

Registry Numbers

CAS Registry Number

  • 10329-96-1

System Generated Number

  • 0010329961

Structure Descriptors

InChI

1S/C18H19N3O5/c22-15-9-12(10-16(23)20(15)11-19-5-7-26-8-6-19)21-17(24)13-3-1-2-4-14(13)18(21)25/h1-4,12H,5-11H2

InChIKey

FDOBAWPDCWCNRJ-UHFFFAOYSA-N

Smiles

C1(N(C(c2ccccc12)=O)C1CC(N(C(C1)=O)CN1CCOCC1)=O)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 4250mg/kg (4250mg/kg) ENDOCRINE: CHANGE IN LH

ENDOCRINE: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 194, Pg. 39, 1971.
mouse LD50 oral > 8gm/kg (8000mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 194, Pg. 39, 1971.
rat LD50 intraperitoneal 1620mg/kg (1620mg/kg) ENDOCRINE: CHANGE IN LH

ENDOCRINE: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 194, Pg. 39, 1971.
rat LD50 oral > 8gm/kg (8000mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 194, Pg. 39, 1971.