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Substance Name: Ondansetron hydrochloride [USAN:USP:JAN]
RN: 103639-04-9
UNII: NMH84OZK2B
InChIKey: VRSLTNZJOUZKLX-UHFFFAOYSA-N

Note

  • A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Molecular Formula

  • C18-H19-N3-O.Cl-H.2H2-O

Molecular Weight

  • 365.8586
 

Classification Codes

  • Anti-Anxiety Agent
  • Anti-Anxiety Agents
  • Anti-Emetic
  • Antischizophrenic

Names and Synonyms

Name of Substance

  • Ondansetron hydrochloride [USAN:USP:JAN]

Synonyms

  • (+-)-2,3-Dihydro-9-methyl-3-((2-methylimidazol-1-yl)methyl)carbazol-4(1H)-one monohydrochloride dihydrate
  • 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-, monohydrochloride, (+-)-, dihydrate
  • GR 38032F
  • Ondansetron hydrochloride
  • Ondansetron hydrochloride dihydrate
  • UNII-NMH84OZK2B
  • Zofran

Systematic Name

  • 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-, monohydrochloride, (+-)-, dihydrate

Registry Numbers

CAS Registry Number

  • 103639-04-9

FDA UNII

  • NMH84OZK2B

Related Registry Number

  • 99614-02-5 (Parent)

System Generated Number

  • 0103639049

Molecular Formulas

Molecular Formula

  • C18-H19-N3-O.Cl-H.2H2-O

Molecular Formula Fragments

  • C18-H19-N3-O
  • Cl-H
  • COMPONENT
  • H2-O

Structure Descriptors

InChI

1S/C18H19N3O.ClH.2H2O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2;;;/h3-6,9-10,13H,7-8,11H2,1-2H3;1H;2*1H2

InChIKey

VRSLTNZJOUZKLX-UHFFFAOYSA-N

Smiles

O.O.Cl.Cc1nccn1CC2CCc3c(C2=O)c4ccccc4n3C