Important Announcement

X

ChemIDplus is moving to PubChem in December 2022.
Please see the NLM Technical Bulletin article for more information.

Skip Navigation
ChemIDplus LiteBrowseAdvanced

Substance Name: Gimeracil [INN]
RN: 103766-25-2
UNII: UA8SE1325T
InChIKey: ZPLQIPFOCGIIHV-UHFFFAOYSA-N

Notes

  • A biochemical and pharmacological modulator of 5-FU.
  • A biochemical and pharmacological modulator of 5-FU.

    NCI: A pyridine derivative with antitumor activity. Gimeracil enhances the antitumor activity of fluoropyrimidines by competitively and reversibly inhibiting the enzyme dihydropyrimidine dehydrogenase causing decreased degradation of the fluoropyrimidines. (NCI Thesaurus)
  • NCI: A pyridine derivative with antitumor activity. Gimeracil enhances the antitumor activity of fluoropyrimidines by competitively and reversibly inhibiting the enzyme dihydropyrimidine dehydrogenase causing decreased degradation of the fluoropyrimidines. (NCI Thesaurus)

Molecular Formula

  • C5-H4-Cl-N-O2

Molecular Weight

  • 145.545
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Gimeracil
  • Gimeracil [INN]

Synonyms

  • 5-Chloro-2,4-dihydroxypyridine
  • 5-Chloro-2,4-pyridinediol
  • 5-Chloro-4-hydroxy-2(1H)-pyridinone
  • Cdhp compound
  • Gimeracil
  • Gimestat
  • UNII-UA8SE1325T

Systematic Name

  • 2(1H)-Pyridinone, 5-chloro-4-hydroxy-

Registry Numbers

CAS Registry Number

  • 103766-25-2

FDA UNII

  • UA8SE1325T

System Generated Number

  • 0103766252

Structure Descriptors

InChI

InChI=1S/C5H4ClNO2/c6-3-2-7-5(9)1-4(3)8/h1-2H,(H2,7,8,9)

InChIKey

ZPLQIPFOCGIIHV-UHFFFAOYSA-N

Smiles

OC1=CC(=O)NC=C1Cl