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Substance Name: p-Anisidine
RN: 104-94-9
UNII: 575917SNR4
InChIKey: BHAAPTBBJKJZER-UHFFFAOYSA-N

Molecular Formula

  • C7-H9-N-O

Molecular Weight

  • 123.1541
 

Classification Codes

Classification Codes

  • Drug / Therapeutic Agent
  • Mutation Data
  • Tumor Data

Superlist Classification Codes

  • Overall Carcinogenic Evaluation: Group 3
  • TWA (0.5 mg/m3); Skin; Not classifiable as a human carcinogen; BEI

Names and Synonyms

Results Name

  • p-Anisidine

Name of Substance

  • 4-Anisidine
  • p-Anisidine

Synonyms

  • 1-Amino-4-methoxybenzene
  • 4-Aminoanisole
  • 4-Anisidine
  • 4-Methoxy-1-aminobenzene
  • 4-Methoxyaniline
  • 4-Methoxybenzenamine
  • 4-Methoxybenzeneamine
  • AI3-02392
  • Aniline, 4-methoxy-
  • Aniline, p-methoxy-
  • Anisole, p-amino-
  • Benzenamine, 4-methoxy-
  • CCRIS 917
  • EINECS 203-254-2
  • HSDB 1603
  • NSC 7921
  • p-Aminoanisole
  • p-Anisidine
  • p-Anisylamine
  • p-Dianisidine
  • p-Methoxyaniline
  • p-Methoxyphenylamine
  • UNII-575917SNR4

Systematic Names

  • Benzenamine, 4-methoxy-
  • p-Anisidine

Superlist Names

  • Aniline, 4-methoxy-
  • Benzenamine, 4-methoxy-
  • p-Anisidine

Registry Numbers

CAS Registry Number

  • 104-94-9

FDA UNII

  • 575917SNR4

Related Registry Number

  • 20265-97-8 (hydrochloride)

System Generated Number

  • 0000104949

Structure Descriptors

InChI

1S/C7H9NO/c1-9-7-4-2-6(8)3-5-7/h2-5H,8H2,1H3

InChIKey

BHAAPTBBJKJZER-UHFFFAOYSA-N

Smiles

COc1ccc(N)cc1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 806mg/kg (806mg/kg)   Journal of Medicinal Chemistry. Vol. 17, Pg. 900, 1974.
mouse LD50 oral 1410mg/kg (1410mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: ATAXIA

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 184, 1992.
rabbit LD50 oral 2900mg/kg (2900mg/kg) BLOOD: OTHER CHANGES

BLOOD: NORMOCYTIC ANEMIA

KIDNEY, URETER, AND BLADDER: OTHER CHANGES
IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. Vol. 27, Pg. 63, 1982.
rat LD50 intraperitoneal 1400mg/kg (1400mg/kg)   Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 15, Pg. 447, 1957.
rat LD50 oral 1320mg/kg (1320mg/kg)   Trudy Leningradskogo Sanitarno-Gigienicheskogo Meditsinskogo Instituta. Vol. 128, Pg. 14, 1979.
rat LD50 skin 3200mg/kg (3200mg/kg)   Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 15, Pg. 447, 1957.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 57.2 deg C   EXP
Boiling Point 243 deg C   EXP
pKa Dissociation Constant 5.34 (none) 25 EXP
log P (octanol-water) 0.95 (none)   EXP
Water Solubility 2.10E+04 mg/L 20 EXP
Vapor Pressure 0.03 mm Hg 20 EXP
Henry's Law Constant 6.60E-08 atm-m3/mole 25 EXP
Atmospheric OH Rate Constant 9.39E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.