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Substance Name: Agalsidase alfa [USAN:INN:BAN]
RN: 104138-64-9

Note

  • Fenetically engineered, glycosylated human alpha-galactosidase isoenzyme A used in treatment of Fabry disease.

Molecular Formula

  • Unspecified
 

Classification Codes

  • Therapeutic Enzymes
  • Treatment of Fabry Disease

Names and Synonyms

Name of Substance

  • Agalsidase alfa
  • Agalsidase alfa [USAN:INN:BAN]
  • Agalsidase beta [INN]

Synonyms

  • Agalsidase alfa
  • Agalsidase beta
  • alpha-Galactosidase (human clone lambdaAG(sup 18) isoenzyme A subunit protein moiety reduced), glycoform beta
  • alpha-Galactosidase (human-clone lambdaAG(sup 18) isoenzyme A subunit protein moiety reduced). Molecular weight is approximately 45,351 daltons
  • Alpha-galactosidase A
  • EC 3.2.1.22
  • Fabrazyme
  • Galactosidase, alpha- (CHO cell line CTH-158 plasmid PGB86)
  • Galactosidase, alpha- (human clone lambdaAG18 isoenzyme A subunit protein moiety reduced)
  • Galactosidase, alpha- (human Clone PGB73)
  • Galactosidase, alpha- (human isoenzyme A reduced)
  • Replagal
  • UNII-2HLC17MX9G
  • UNII-RZD65TSM9U

Systematic Name

  • Galactosidase, alpha-(human clone lambdaAG18 isoenzyme A subunit protein moiety reduced)

Registry Numbers

CAS Registry Number

  • 104138-64-9

FDA UNIIs

  • 2HLC17MX9G
  • RZD65TSM9U

System Generated Number

  • 0104138649