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Substance Name: Famciclovir [USAN:INN:BAN]
RN: 104227-87-4
UNII: QIC03ANI02
InChIKey: GGXKWVWZWMLJEH-UHFFFAOYSA-N

Note

  • Prodrug of penciclovir; phosphorylated by viral thymidine kinase and subsequently cellular kinases to a penciclovir triphosphate, which inhibits herpes simplex 2 DNA polymerase in a competitive manner.

Molecular Formula

  • C14-H19-N5-O4

Molecular Weight

  • 321.335
 

Classification Codes

  • Anti-Infective Agents
  • Antiviral
  • Antiviral Agents

Names and Synonyms

Name of Substance

  • Famciclovir
  • Famciclovir [USAN:INN:BAN]

Synonyms

  • 2-(2-(2-Amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate (ester)
  • BRL 42810
  • BRL-42810
  • Famciclovir
  • Famciclovirum
  • Famciclovirum [INN-Latin]
  • Famvir
  • HSDB 8121
  • UNII-QIC03ANI02

Systematic Name

  • 1,3-Propanediol, 2-(2-(2-amino-9H-purin-9-yl)ethyl)-, diacetate (ester)

Registry Numbers

CAS Registry Number

  • 104227-87-4

FDA UNII

  • QIC03ANI02

System Generated Number

  • 0104227874

Structure Descriptors

InChI

1S/C14H19N5O4/c1-9(20)22-6-11(7-23-10(2)21)3-4-19-8-17-12-5-16-14(15)18-13(12)19/h5,8,11H,3-4,6-7H2,1-2H3,(H2,15,16,18)

InChIKey

GGXKWVWZWMLJEH-UHFFFAOYSA-N

Smiles

c12n(cnc1cnc(n2)N)CCC(COC(C)=O)COC(C)=O