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Substance Name: Apabetalone [USAN:INN]
RN: 1044870-39-4
UNII: 8R4A7GDZ1D
InChIKey: NETXMUIMUZJUTB-UHFFFAOYSA-N
Notes
- A bromodomain and extra-terminal domain protein (BET) inhibitor; prevents interactions between BET proteins and acetyl-lysine residues on histone tails to modify epigenetic regulation.
- An antiatheriosclerotic agent that inhibits amyloid protein deposition.
Molecular Formula
- C20-H22-N2-O5
Molecular Weight
- 370.4028
Classification Codes
- Antiviral (COVID-19)
- Treatment of Atherosclerosis and Cardiovascular Disease
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Names and Synonyms
Results Name
- Apabetalone [USAN:INN]
Name of Substance
- Apabetalone [INN]
- Apabetalone [USAN:INN]
- RVX-000222
Synonyms
- 2-(4-(2-hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxy-4(1H)-quinazolinone
- 2-(4-(2-Hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxyquinazolin-4(3H)-one
- Apabetalone
- RVX 000222
- RVX 208
- RVX-208
- RVX000222
- RVX208
- UNII-8R4A7GDZ1D
Registry Numbers
CAS Registry Number
- 1044870-39-4
FDA UNII
- 8R4A7GDZ1D
Other Registry Number
- 1246400-89-4
System Generated Number
- 1044870394