Skip Navigation
ChemIDplus LiteBrowseAdvanced

Substance Name: Apabetalone [USAN:INN]
RN: 1044870-39-4
UNII: 8R4A7GDZ1D
InChIKey: NETXMUIMUZJUTB-UHFFFAOYSA-N

Notes

  • A bromodomain and extra-terminal domain protein (BET) inhibitor; prevents interactions between BET proteins and acetyl-lysine residues on histone tails to modify epigenetic regulation.
  • An antiatheriosclerotic agent that inhibits amyloid protein deposition.

Molecular Formula

  • C20-H22-N2-O5

Molecular Weight

  • 370.4028
 

Classification Codes

  • Antiviral (COVID-19)
  • Treatment of Atherosclerosis and Cardiovascular Disease
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Results Name

  • Apabetalone [USAN:INN]

Name of Substance

  • Apabetalone [INN]
  • Apabetalone [USAN:INN]
  • RVX-000222

Synonyms

  • 2-(4-(2-hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxy-4(1H)-quinazolinone
  • 2-(4-(2-Hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxyquinazolin-4(3H)-one
  • Apabetalone
  • RVX 000222
  • RVX 208
  • RVX-208
  • RVX000222
  • RVX208
  • UNII-8R4A7GDZ1D

Registry Numbers

CAS Registry Number

  • 1044870-39-4

FDA UNII

  • 8R4A7GDZ1D

Other Registry Number

  • 1246400-89-4

System Generated Number

  • 1044870394

Structure Descriptors

InChI

InChI=1S/C20H22N2O5/c1-11-7-13(8-12(2)18(11)27-6-5-23)19-21-15-9-14(25-3)10-16(26-4)17(15)20(24)22-19/h7-10,23H,5-6H2,1-4H3,(H,21,22,24)

InChIKey

NETXMUIMUZJUTB-UHFFFAOYSA-N

Smiles

COc1cc(OC)c2C(=O)NC(=Nc2c1)c3cc(C)c(OCCO)c(C)c3