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Substance Name: Fibroblast growth factor, acidic
RN: 104781-85-3

Note

  • A 17-kDa single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. It binds to HEPARIN, which potentiates its biological activity and protects it from proteolysis. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages, and also has chemotactic and mitogenic activities. It was originally named acidic fibroblast growth factor based upon its chemical properties and to distinguish it from basic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 2).
 
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Names and Synonyms

Name of Substance

  • Fibroblast growth factor, acidic

MeSH Heading

  • Fibroblast growth factor 1

Synonyms

  • Acidic fibroblast growth factor
  • Class I heparin-binding growth factor
  • Hbgf-1
  • Heparin-binding fibroblast growth factor class I
  • Heparin-binding growth factor, class I

Systematic Name

  • Fibroblast growth factor (human brain acidic protein moiety reduced)

Registry Numbers

CAS Registry Number

  • 104781-85-3

System Generated Number

  • 0104781853