Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Osteocalcin
RN: 104982-03-8


  • Vitamin K-dependent calcium-binding protein synthesized by OSTEOBLASTS and found primarily in BONES. Serum osteocalcin measurements provide a noninvasive specific marker of bone metabolism. The protein contains three residues of the amino acid gamma-carboxyglutamic acid (Gla), which, in the presence of CALCIUM, promotes binding to HYDROXYAPATITE and subsequent accumulation in BONE MATRIX.

Molecular Formula

  • C229-H353-N57-O80-S2
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)

Names and Synonyms

Name of Substance

  • Osteocalcin

MeSH Heading

  • Osteocalcin


  • Bone gla protein
  • Calcium-binding protein, vitamin K-dependent
  • Gla protein, bone
  • Osteocalcin
  • Vitamin K-dependent bone protein

Systematic Names

  • ne-49-L-Threonine-49a-L-isoleucine-
  • Osteocalcin (human reduced),
  • Osteocalcin (human reduced), 3-de-L-Tyrosine-4-de-L-glutamine-5-de-L-tryptophan-6-de-L-leucine-9-L-serine-12-L-serine-19-L-threonine-22-L-glutamine-28-L-alanine-33-L-serine-35-L-glutamine-36-L-tyrosine-38-L-leucine-39-L-lysine-40-L-threonine-43-L-lysine-45-L-isoleucine-48-L-isoleucine-49-L-threonine-49a-L-isoleucine-

Registry Numbers

CAS Registry Number

  • 104982-03-8

System Generated Number

  • 0104982038