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Substance Name: Amuvatinib hydrochloride [USAN]
RN: 1055986-67-8
UNII: 14L8O2K12B
InChIKey: IKQFRXPMBGQJGE-UHFFFAOYSA-N

Note

  • c-Kit/AXL tyrosine kinase inhibitor that synergizes with docetaxel (taxotere) and is cytotoxic to gastrointestinal stromal tumor cells.

Molecular Weight

  • 483.9778
 

Classification Code

  • Treatment of Cancer
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Names and Synonyms

Name of Substance

  • Amuvatinib hydrochloride [USAN]

Synonyms

  • Amuvatinib hydrochloride
  • HPK56
  • MP-470.HCL
  • MP470.HCL
  • UNII-14L8O2K12B

Registry Numbers

CAS Registry Number

  • 1055986-67-8

FDA UNII

  • 14L8O2K12B

System Generated Number

  • 1055986678

Structure Descriptors

InChI

1S/C23H21N5O3S.ClH/c32-23(24-12-15-5-6-18-19(11-15)30-14-29-18)28-9-7-27(8-10-28)22-21-20(25-13-26-22)16-3-1-2-4-17(16)31-21;/h1-6,11,13H,7-10,12,14H2,(H,24,32);1H

InChIKey

IKQFRXPMBGQJGE-UHFFFAOYSA-N

Smiles

Cl.S=C(NCc1ccc2OCOc2c1)N3CCN(CC3)c4ncnc5c4oc6ccccc56