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Substance Name: 4-Xylene
RN: 106-42-3
UNII: 6WAC1O477V
InChIKey: URLKBWYHVLBVBO-UHFFFAOYSA-N

Molecular Formula

  • C8-H10

Molecular Weight

  • 106.167
 

Classification Codes

Classification Code

  • Reproductive Effect

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 185
  • 2011 CERCLA Priority List, Rank: 180
  • Overall Carcinogenic Evaluation: Group 3
  • Reportable Quantity (RQ) = 100 lb
  • TWA (100 ppm); STEL (150 ppm); Not classifiable as a human carcinogen; BEI
  • TWA 100 mg/m3 (435 ppm)

Names and Synonyms

Name of Substance

  • 4-Xylene

Synonyms

  • 1,4-Dimethylbenzene
  • 1,4-Xylene
  • 4-Xylene
  • AI3-52255
  • Benzene, 1,4-dimethyl-
  • CCRIS 910
  • Chromar
  • EC 203-396-5
  • EINECS 203-396-5
  • HSDB 136
  • NSC 72419
  • p-Dimethylbenzene
  • p-Methyltoluene
  • p-Xylene
  • p-Xylol
  • Scintillar
  • UNII-6WAC1O477V

Systematic Names

  • Benzene, 1,4-dimethyl-
  • p-Xylene

Superlist Names

  • Benzene, 1,4-dimethyl-
  • Benzene, p-dimethyl-
  • p-Xylene
  • p-Xylene [UN1307] [Flammable liquid]
  • UN1307
  • Xylene, p-
  • Xylene, p-isomer

Registry Numbers

CAS Registry Number

  • 106-42-3

FDA UNII

  • 6WAC1O477V

System Generated Number

  • 0000106423

Structure Descriptors

InChI

1S/C8H10/c1-7-3-5-8(2)6-4-7/h3-6H,1-2H3

InChIKey

URLKBWYHVLBVBO-UHFFFAOYSA-N

Smiles

c1(ccc(C)cc1)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LC inhalation > 8350ppm/4H (8350ppm) BEHAVIORAL: ATAXIA

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: TREMOR
National Technical Information Service. Vol. OTS0556752,
mammal (species unspecified) LDLo intraperitoneal 2gm/kg (2000mg/kg)   Journal of Pathology and Bacteriology. Vol. 46, Pg. 95, 1938.
mammal (species unspecified) LDLo subcutaneous 5gm/kg (5000mg/kg)   Journal of Pathology and Bacteriology. Vol. 46, Pg. 95, 1938.
mouse LCLo inhalation 15gm/m3 (15000mg/m3) BEHAVIORAL: GENERAL ANESTHETIC

CARDIAC: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 143, Pg. 223, 1929.
mouse LD50 intraperitoneal 2450uL/kg (2.45mL/kg)   Archives of Toxicology. Vol. 58, Pg. 106, 1985.
rat LC50 inhalation 4550ppm/4H (4550ppm) LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA

BLOOD: CHANGES IN CELL COUNT (UNSPECIFIED)

LIVER: OTHER CHANGES
"Biological Reactive Intermediates, Formation, Toxicity and Inactivation, Proceedings of the International Conference, Turku, Finland, 1975," Jollow, D.J., et al., eds., New York, Plenum Pub. Corp., 1977Vol. -, Pg. 302, 1977.
rat LD50 intraperitoneal 3810mg/kg (3810mg/kg) LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA

BLOOD: CHANGES IN CELL COUNT (UNSPECIFIED)

LIVER: OTHER CHANGES
"Biological Reactive Intermediates, Formation, Toxicity and Inactivation, Proceedings of the International Conference, Turku, Finland, 1975," Jollow, D.J., et al., eds., New York, Plenum Pub. Corp., 1977Vol. -, Pg. 302, 1977.
rat LD50 oral 5gm/kg (5000mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 22, Pg. 883, 1980.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 13.2 deg C   EXP
Boiling Point 138.3 deg C   EXP
log P (octanol-water) 3.15 (none)   EXP
Water Solubility 162 mg/L 25 EXP
Vapor Pressure 8.84 mm Hg 25 EXP
Henry's Law Constant 0.0069 atm-m3/mole 25 EXP
Atmospheric OH Rate Constant 1.43E-11 cm3/molecule-sec 25 EXP

Physical property data is provided to ChemIDplus by SRC, Inc.