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Substance Name: 4-Xylene
RN: 106-42-3
UNII: 6WAC1O477V
InChIKey: URLKBWYHVLBVBO-UHFFFAOYSA-N

Molecular Formula

  • C8-H10

Molecular Weight

  • 106.167
 

Classification Codes

Classification Code

  • Reproductive Effect

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 185
  • 2011 CERCLA Priority List, Rank: 180
  • Overall Carcinogenic Evaluation: Group 3
  • Reportable Quantity (RQ) = 100 lb
  • TWA (100 ppm); STEL (150 ppm); Not classifiable as a human carcinogen; BEI
  • TWA 100 mg/m3 (435 ppm)

Names and Synonyms

Name of Substance

  • 4-Xylene

Synonyms

  • 1,4-Dimethylbenzene
  • 1,4-Xylene
  • 4-Xylene
  • AI3-52255
  • Benzene, 1,4-dimethyl-
  • CCRIS 910
  • Chromar
  • EC 203-396-5
  • EINECS 203-396-5
  • HSDB 136
  • NSC 72419
  • p-Dimethylbenzene
  • p-Methyltoluene
  • p-Xylene
  • p-Xylol
  • Scintillar
  • UNII-6WAC1O477V

Systematic Names

  • Benzene, 1,4-dimethyl-
  • p-Xylene

Superlist Names

  • Benzene, 1,4-dimethyl-
  • Benzene, p-dimethyl-
  • p-Xylene
  • p-Xylene [UN1307] [Flammable liquid]
  • UN1307
  • Xylene, p-
  • Xylene, p-isomer

Registry Numbers

CAS Registry Number

  • 106-42-3

FDA UNII

  • 6WAC1O477V

System Generated Number

  • 0000106423

Structure Descriptors

InChI

1S/C8H10/c1-7-3-5-8(2)6-4-7/h3-6H,1-2H3

InChIKey

URLKBWYHVLBVBO-UHFFFAOYSA-N

Smiles

c1(ccc(C)cc1)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LC inhalation > 8350ppm/4H (8350ppm) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: TREMOR

BEHAVIORAL: ATAXIA
National Technical Information Service. Vol. OTS0556752,
mammal (species unspecified) LDLo intraperitoneal 2gm/kg (2000mg/kg)   Journal of Pathology and Bacteriology. Vol. 46, Pg. 95, 1938.
mammal (species unspecified) LDLo subcutaneous 5gm/kg (5000mg/kg)   Journal of Pathology and Bacteriology. Vol. 46, Pg. 95, 1938.
mouse LCLo inhalation 15gm/m3 (15000mg/m3) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

CARDIAC: OTHER CHANGES

BEHAVIORAL: GENERAL ANESTHETIC
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 143, Pg. 223, 1929.
mouse LD50 intraperitoneal 2450uL/kg (2.45mL/kg)   Archives of Toxicology. Vol. 58, Pg. 106, 1985.
rat LC50 inhalation 4550ppm/4H (4550ppm) LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA

LIVER: OTHER CHANGES

BLOOD: CHANGES IN CELL COUNT (UNSPECIFIED)
"Biological Reactive Intermediates, Formation, Toxicity and Inactivation, Proceedings of the International Conference, Turku, Finland, 1975," Jollow, D.J., et al., eds., New York, Plenum Pub. Corp., 1977Vol. -, Pg. 302, 1977.
rat LD50 intraperitoneal 3810mg/kg (3810mg/kg) LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA

BLOOD: CHANGES IN CELL COUNT (UNSPECIFIED)

LIVER: OTHER CHANGES
"Biological Reactive Intermediates, Formation, Toxicity and Inactivation, Proceedings of the International Conference, Turku, Finland, 1975," Jollow, D.J., et al., eds., New York, Plenum Pub. Corp., 1977Vol. -, Pg. 302, 1977.
rat LD50 oral 5gm/kg (5000mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 22, Pg. 883, 1980.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 13.2 deg C   EXP
Boiling Point 138.3 deg C   EXP
log P (octanol-water) 3.15 (none)   EXP
Water Solubility 162 mg/L 25 EXP
Vapor Pressure 8.84 mm Hg 25 EXP
Henry's Law Constant 0.0069 atm-m3/mole 25 EXP
Atmospheric OH Rate Constant 1.43E-11 cm3/molecule-sec 25 EXP

Physical property data is provided to ChemIDplus by SRC, Inc.