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Substance Name: p-Toluidine
RN: 106-49-0
UNII: I1D0KL7I4U
InChIKey: RZXMPPFPUUCRFN-UHFFFAOYSA-N

Molecular Formula

  • C7-H9-N

Molecular Weight

  • 107.1551
 

Classification Codes

Classification Codes

  • Mutation Data
  • Skin / Eye Irritant

Superlist Classification Codes

  • Reportable Quantity (RQ) = 100 lb
  • TWA (2 ppm); skin; Confirmed animal carcinogen with unknown relevance to humans; BEI

Names and Synonyms

Results Name

  • p-Toluidine

Name of Substance

  • 4-Aminotoluene
  • 4-Toluidine
  • p-Toluidine

Synonyms

  • 1-Amino-4-methylbenzene
  • 4-Amino-1-methylbenzene
  • 4-Aminotoluen
  • 4-Aminotoluen [Czech]
  • 4-Aminotoluene
  • 4-Methylaniline
  • 4-Methylbenzenamine
  • 4-Toluidine
  • AI3-19858
  • Aniline, p-methyl-
  • Benzenamine, 4-methyl-
  • C.I. 37107
  • C.I. Azoic Coupling Component 107
  • CCRIS 598
  • CI 37107
  • CI Azoic Coupling Component 107
  • EC 203-403-1
  • EINECS 203-403-1
  • HSDB 2044
  • Naphtol AS-KG
  • Naphtol AS-KGLL
  • NSC 15350
  • p-Aminotoluene
  • p-Methylaniline
  • p-Methylbenzenamine
  • p-Toluidin
  • p-Toluidin [Czech]
  • p-Toluidine
  • p-Toluidyna
  • p-Toluidyna [Polish]
  • p-Tolylamine
  • RCRA waste number U353
  • Toluidine, p-
  • UNII-I1D0KL7I4U

Systematic Names

  • Benzenamine, 4-methyl-
  • p-Toluidine

Superlist Names

  • Benzenamine, 4-methyl-
  • p-Toluidine
  • p-Toluidine, liquid or solid
  • p-Toluidine, liquid or solid [UN1708] [Poison]
  • RCRA waste no. U353
  • UN1708

Registry Numbers

CAS Registry Number

  • 106-49-0

FDA UNII

  • I1D0KL7I4U

Other Registry Number

  • 12221-03-3

Related Registry Numbers

  • 32954-54-4 (nitrate)
  • 540-23-8 (hydrochloride)

System Generated Number

  • 0000106490

Structure Descriptors

InChI

1S/C7H9N/c1-6-2-4-7(8)5-3-6/h2-5H,8H2,1H3

InChIKey

RZXMPPFPUUCRFN-UHFFFAOYSA-N

Smiles

Cc1ccc(cc1)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 42mg/kg (42mg/kg)   Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972.
mouse LD50 intraperitoneal 50mg/kg (50mg/kg)   National Technical Information Service. Vol. AD691-490,
mouse LD50 oral 330mg/kg (330mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 25(8), Pg. 50, 1981.
quail LD50 oral 237mg/kg (237mg/kg)   Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
rabbit LD50 oral 270mg/kg (270mg/kg)   Vsesoyuznyi Institut Nauchnoi i Tekhnicheskoi Informatsii Vol. #4035-77,
rabbit LD50 skin 890mg/kg (890mg/kg)   BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 31-4/1973,
rat LC50 inhalation > 640mg/m3/1H (640mg/m3)   BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 31-4/1973,
rat LD50 oral 336mg/kg (336mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Bromatologia i Chemia Toksykologiczna. Vol. 17, Pg. 51, 1984.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 43.7 deg C   EXP
Boiling Point 200.4 deg C   EXP
pKa Dissociation Constant 5.1 (none) 25 EXP
log P (octanol-water) 1.39 (none)   EXP
Water Solubility 6500 mg/L 15 EXP
Vapor Pressure 0.286 mm Hg 25 EXP
Henry's Law Constant 2.02E-06 atm-m3/mole 25 EXP
Atmospheric OH Rate Constant 1.32E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.