|
|
Substance Name: Ethylene dibromide [BSI:ISO]
RN: 106-93-4
UNII: 1N41638RNO
InChIKey: PAAZPARNPHGIKF-UHFFFAOYSA-N
Note
- An effective soil fumigant, insecticide, and nematocide. In humans, it causes severe burning of skin and irritation of the eyes and respiratory tract. Prolonged inhalation may cause liver necrosis. It is also used in gasoline. Members of this group have caused liver and lung cancers in rodents. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), 1,2-dibromoethane may reasonably be anticipated to be a carcinogen.
Molecular Formula
- C2-H4-Br2
Molecular Weight
- 187.862
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Agricultural Chemical
- Fungicide, Bactericide, Wood Preservative
- Human Data
- Insecticide
- Mutation Data
- Nematocide
- Reproductive Effect
- Skin / Eye Irritant
- Tumor Data
Superlist Classification Codes
- 2007 CERCLA Priority List, Rank: 35
- 2011 CERCLA Priority List, Rank: 39
- Overall Carcinogenic Evaluation: Group 2A
- Reasonably Anticipated to be a Carcinogen
- Reportable Quantity (RQ) = 1 lb
- Skin; Confirmed Animal Carcinogen with Unknown Relevance to Humans
- TWA 20 mg/m3; Ceiling 30 mg/m3, peak 50 mg/m3 in 5 min
* denotes mobile formatted website
Links to Resources
NLM Resources (File Locators)
Regulatory Agencies (Superlist Locators)
Other Resources (Internet Locators)
Search for this InChIKey on the Web
Names and Synonyms
Results Name
- Ethylene dibromide [BSI:ISO]
Name of Substance
- Ethylene dibromide
- Ethylene dibromide [BSI:ISO]
MeSH Heading
- Ethylene dibromide
Synonyms
- 1,2-Dibromaethan
- 1,2-Dibromaethan [German]
- 1,2-Dibromoetano
- 1,2-Dibromoetano [Italian]
- 1,2-Dibromoethane
- 1,2-Dibroomethaan
- 1,2-Dibroomethaan [Dutch]
- 1,2-Ethylene dibromide
- 4-01-00-00158 (Beilstein Handbook Reference)
- Aadibroom
- Aethylenbromid
- Aethylenbromid [German]
- AI3-15349
- alpha,beta-Dibromoethane
- alpha,omega-Dibromoethane
- BRN 0605266
- Bromofume
- Bromuro di etile
- Bromuro di etile [Italian]
- Caswell No. 439
- CCRIS 295
- Celmide
- Dibromure d'ethylene
- Dibromure d'ethylene [French]
- Dibromure d'ethylene [ISO-French]
- Dowfume 40
- Dowfume EDB
- Dowfume W-100
- Dowfume W-8
- Dowfume W-85
- Dowfume W-90
- Dwubromoetan
- Dwubromoetan [Polish]
- E-D-Bee
- EC 203-444-5
- Edabrom
- EDB
- EDB-85
- EINECS 203-444-5
- ENT 15,349
- EPA Pesticide Chemical Code 042002
- Ethane, 1,2-dibromo-
- Ethylene bromide
- Ethylene dibromide
- Fumo-gas
- Glycol dibromide
- HSDB 536
- Iscobrome D
- Kopfume
- NCI-C00522
- Nefis
- Nephis
- Pestmaster edb-85
- RCRA waste number U067
- Sanhyuum
- Soilbrom
- Soilbrom-100
- Soilbrom-40
- Soilbrom-85
- Soilbrom-90
- Soilbrom-90EC
- Soilfume
- sym-Dibromoethane
- UN 1605
- Unifume
- UNII-1N41638RNO
Systematic Names
- 1,2-Dibromoethane
- Ethane, 1,2-dibromo-
- Ethylene dibromide
Superlist Names
- 1,2-Dibromoethane
- Dibromoethane
- EDB
- Ethane, 1,2-dibromo-
- Ethylene dibromide
- Ethylene dibromide [UN1605] [Poison]
- RCRA waste no. U067
- UN1605
Registry Numbers
CAS Registry Number
- 106-93-4
FDA UNII
- 1N41638RNO
Other Registry Numbers
- 56729-21-6
- 625084-37-9
- 8003-07-4
System Generated Number
- 0000106934
Structure Descriptors
InChI
InChI=1S/C2H4Br2/c3-1-2-4/h1-2H2InChIKey
PAAZPARNPHGIKF-UHFFFAOYSA-NSmiles
BrCCBrToxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
chicken | LD50 | oral | 79mg/kg (79mg/kg) | AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 6, Pg. 158, 1952. | |
guinea pig | LCLo | inhalation | 400ppm/3H (400ppm) | AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 6, Pg. 158, 1952. | |
guinea pig | LCLo | inhalation | 400ppm/3H (400ppm) | LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), ZONAL" | AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 6, Pg. 158, 1952. |
guinea pig | LD50 | oral | 110mg/kg (110mg/kg) | AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 6, Pg. 158, 1952. | |
man | TDLo | oral | 43uL/kg (0.043mL/kg) | KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED" | Human & Experimental Toxicology. Vol. 19, Pg. 152, 2000. |
mouse | LD50 | intraperitoneal | 220mg/kg (220mg/kg) | Journal fuer Praktische Chemie. Vol. 320, Pg. 133, 1978. | |
mouse | LD50 | unreported | 146mg/kg (146mg/kg) | "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 38, 1971. | |
mouse | LDLo | oral | 250mg/kg (250mg/kg) | Toxicology and Applied Pharmacology. Vol. 23, Pg. 288, 1972. | |
quail | LD50 | oral | 130mg/kg (130mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | British Poultry Science. Vol. 22, Pg. 355, 1981. |
rabbit | LD50 | oral | 55mg/kg (55mg/kg) | AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 6, Pg. 158, 1952. | |
rabbit | LD50 | skin | 300mg/kg (300mg/kg) | AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 6, Pg. 158, 1952. | |
rabbit | LD50 | skin | 300mg/kg (300mg/kg) | SKIN AND APPENDAGES (SKIN): CORROSIVE: AFTER TOPICAL EXPOSURE | AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 6, Pg. 158, 1952. |
rabbit | LDLo | rectal | 2500mg/kg (2500mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE" | Journal of Pharmacology and Experimental Therapeutics. Vol. 34, Pg. 223, 1928. |
rat | LC50 | inhalation | 14300mg/m3/30 (14300mg/m3) | PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Farmakologiya i Toksikologiya Vol. 8, Pg. 140, 1973. |
rat | LD50 | oral | 108mg/kg (108mg/kg) | Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 17, 1978. | |
rat | LD50 | skin | 300mg/kg (300mg/kg) | "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976Vol. -, Pg. -, 1971/1976. | |
women | LDLo | oral | 90mg/kg (90mg/kg) | GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED GASTROINTESTINAL: NAUSEA OR VOMITING | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 257, 1969. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 9.9 | deg C | EXP | |
Boiling Point | 131.6 | deg C | EXP | |
log P (octanol-water) | 1.96 | (none) | EXP | |
Water Solubility | 3910 | mg/L | 25 | EXP |
Vapor Pressure | 11.2 | mm Hg | 25 | EXP |
Henry's Law Constant | 6.50E-04 | atm-m3/mole | 25 | EXP |
Atmospheric OH Rate Constant | 2.50E-13 | cm3/molecule-sec | 25 | EXP |
Physical property data is provided to ChemIDplus by SRC, Inc.