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Substance Name: Rufloxacin hydrochloride
RN: 106017-08-7
UNII: 1643374N6L
InChIKey: LPQOADBMXVRBNX-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C17-H18-F-N3-O3-S.Cl-H

Molecular Weight

  • 399.8721
 
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Names and Synonyms

Name of Substance

  • Rufloxacin hydrochloride

Synonyms

  • MF-934
  • UNII-1643374N6L

Systematic Name

  • 7H-Pyrido(1,2,3-de)(1,4)benzothiazine-6-carboxylic acid, 2,3-dihydro-9-fluoro-10-(4-methyl-1-piperazinyl)-7-oxo-, monohydrochloride

Registry Numbers

CAS Registry Number

  • 106017-08-7

FDA UNII

  • 1643374N6L

Related Registry Number

  • 101363-10-4 (Parent)

System Generated Number

  • 0106017087

Molecular Formulas

Molecular Formula

  • C17-H18-F-N3-O3-S.Cl-H

Molecular Formula Fragments

  • C17-H18-F-N3-O3-S
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C17H18FN3O3S.ClH/c1-19-2-4-20(5-3-19)14-12(18)8-10-13-16(14)25-7-6-21(13)9-11(15(10)22)17(23)24;/h8-9H,2-7H2,1H3,(H,23,24);1H

InChIKey

LPQOADBMXVRBNX-UHFFFAOYSA-N

Smiles

CN1CCN(CC1)c2c(cc3c4c2SCCn4cc(c3=O)C(=O)O)F.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 224mg/kg (224mg/kg)   Journal of Medicinal Chemistry. Vol. 30, Pg. 465, 1987.
rabbit LD50 oral 660mg/kg (660mg/kg)   Journal of Medicinal Chemistry. Vol. 30, Pg. 465, 1987.
rat LD50 intravenous 285mg/kg (285mg/kg)   Journal of Medicinal Chemistry. Vol. 30, Pg. 465, 1987.
rat LD50 oral 501mg/kg (501mg/kg)   Journal of Medicinal Chemistry. Vol. 30, Pg. 465, 1987.