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Substance Name: Sertindole [USAN:INN:BAN]
RN: 106516-24-9
UNII: GVV4Z879SP
InChIKey: GZKLJWGUPQBVJQ-UHFFFAOYSA-N

Molecular Formula

  • C24-H26-Cl-F-N4-O

Molecular Weight

  • 440.9474
 

Classification Codes

  • Antipsychotic
  • Antipsychotic Agents
  • Central Nervous System Agents
  • Central Nervous System Depressants
  • Drug / Therapeutic Agent
  • Human Data
  • Neuroleptic
  • Psychotropic Drugs
  • Tranquilizing Agents
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Names and Synonyms

Name of Substance

  • Sertindole
  • Sertindole [USAN:INN:BAN]

Synonyms

  • 1-(2-(4-(5-Chloro-1-(4-fluorophenyl)-1H-indole-3-yl)-1-piperidinyl)ethyl)-2-imidazolidinone
  • 1-(2-(4-(5-Chloro-1-(p-fluorophenyl)indol-3-yl)piperidino)ethyl)-2-imidazolidinone
  • 2-Imidazolidinone, 1-(2-(4-(5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl)-1-piperidinyl)ethyl)-
  • Lu 23-174
  • SerLect
  • Sertindol
  • Sertindol [INN-Spanish]
  • Sertindole
  • Sertindolum
  • Sertindolum [INN-Latin]
  • UNII-GVV4Z879SP

Systematic Name

  • 2-Imidazolidinone, 1-(2-(4-(5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl)-1-piperidinyl)ethyl)-

Registry Numbers

CAS Registry Number

  • 106516-24-9

FDA UNII

  • GVV4Z879SP

System Generated Number

  • 0106516249

Structure Descriptors

InChI

1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)

InChIKey

GZKLJWGUPQBVJQ-UHFFFAOYSA-N

Smiles

c1cc(ccc1n2cc(c3c2ccc(c3)Cl)C4CCN(CC4)CCN5CCNC5=O)F

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
women TDLo oral 39mg/kg/10W-I (39mg/kg) BEHAVIORAL: ATAXIA British Journal of Psychiatry. Vol. 173, Pg. 351, 1998.