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Substance Name: Adapalene [USAN:INN:BAN]
RN: 106685-40-9
UNII: 1L4806J2QF
InChIKey: LZCDAPDGXCYOEH-UHFFFAOYSA-N

Note

  • A naphthalene derivative that has specificity for RETINOIC ACID RECEPTORS. It is used as a DERMATOLOGIC AGENT for the treatment of ACNE.

Molecular Formula

  • C28-H28-O3

Molecular Weight

  • 412.5262
 

Classification Codes

  • Analgesics
  • Analgesics, Non-Narcotic
  • Anti-Acne
  • Anti-Inflammatory Agents
  • Anti-Inflammatory Agents, Non-Steroidal
  • Antirheumatic Agents
  • Dermatologic Agents
  • Peripheral Nervous System Agents
  • Sensory System Agents

Names and Synonyms

Name of Substance

  • Adapalene
  • Adapalene [USAN:INN:BAN]

MeSH Heading

  • Adapalene

Synonyms

  • 271
  • 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid
  • Adapalen
  • Adapalene
  • Adapaleno
  • Adapaleno [INN-Spanish]
  • Adapalenum
  • Adapalenum [INN-Latin]
  • CD 271
  • Differin
  • Differin Gel
  • Differin Gel 0.1%
  • UNII-1L4806J2QF

Systematic Name

  • 2-Naphthalenecarboxylic acid, 6-(4-methoxy-3-tricyclo(3.3.1.1(sup 3,7))dec-1-ylphenyl)-

Registry Numbers

CAS Registry Number

  • 106685-40-9

FDA UNII

  • 1L4806J2QF

System Generated Number

  • 0106685409

Structure Descriptors

InChI

InChI=1S/C28H28O3/c1-31-26-7-6-23(21-2-3-22-12-24(27(29)30)5-4-20(22)11-21)13-25(26)28-14-17-8-18(15-28)10-19(9-17)16-28/h2-7,11-13,17-19H,8-10,14-16H2,1H3,(H,29,30)

InChIKey

LZCDAPDGXCYOEH-UHFFFAOYSA-N

Smiles

COc1ccc(cc1C23CC4CC(CC(C4)C2)C3)c5ccc6cc(ccc6c5)C(=O)O