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Substance Name: Ethylenediamine [USP:JAN]
RN: 107-15-3
UNII: 60V9STC53F
InChIKey: PIICEJLVQHRZGT-UHFFFAOYSA-N

Note

  • Edamine is the recommended contraction for the ethylenediamine radical.

Molecular Formula

  • C2-H8-N2

Molecular Weight

  • 60.0992
 

Classification Codes

Classification Codes

  • Component of Aminophylline Injection
  • Human Data
  • Mutation Data
  • Reproductive Effect
  • Skin / Eye Irritant

Superlist Classification Codes

  • Reportable Quantity (RQ) = 5000 lb
  • Threshold Planning Quantity (TPQ) = 10000 lb
  • TWA (10 ppm); skin; Not classifiable as a human carcinogen
  • TWA 10 ppm (25 mg/m3)

Names and Synonyms

Name of Substance

  • Edamine [INN]
  • Ethylenediamine
  • Ethylenediamine [USP:JAN]

Synonyms

  • 1,2-Diamino-ethaan
  • 1,2-Diamino-ethaan [Dutch]
  • 1,2-Diamino-ethano
  • 1,2-Diamino-ethano [Italian]
  • 1,2-Diaminoaethan
  • 1,2-Diaminoaethan [German]
  • 1,2-Diaminoethane
  • 1,2-Ethanediamine
  • 1,2-Ethylenediamine
  • 4-04-00-01166 (Beilstein Handbook Reference)
  • Aethaldiamin
  • Aethaldiamin [German]
  • Aethylenediamin
  • Aethylenediamin [German]
  • AI3-24231
  • Algicode 106L
  • Amerstat 274
  • beta-Aminoethylamine
  • BRN 0605263
  • Caswell No. 437
  • CCRIS 5224
  • Dimethylenediamine
  • EC 203-468-6
  • Edamine
  • EINECS 203-468-6
  • EPA Pesticide Chemical Code 004205
  • Ethyleendiamine
  • Ethyleendiamine [Dutch]
  • Ethylendiamine
  • Ethylene-diamine
  • Ethylene-diamine [French]
  • Ethylenediamine
  • HSDB 535
  • NCI-C60402
  • UNII-60V9STC53F

Systematic Names

  • 1,2-Ethanediamine
  • Ethylenediamine

Superlist Names

  • 1,2-Diaminoethane
  • 1,2-Ethanediamine
  • Ethylenediamine
  • Ethylenediamine [UN1604] [Corrosive]
  • UN1604

Mixture Name

  • Aminophylline Injection

Registry Numbers

CAS Registry Number

  • 107-15-3

FDA UNII

  • 60V9STC53F

Other Registry Numbers

  • 8030-24-8
  • 85404-18-8

Related Registry Numbers

  • 14852-17-6 (unspecified phosphate)
  • 15467-15-9 (unspecified hydrochloride)
  • 18299-54-2 (mono-hydrochloride)
  • 20829-66-7 (dinitrate)
  • 22029-36-3 (sulfate[1:1])
  • 25723-52-8 (unspecified sulfate)
  • 333-18-6 (di-hydrochloride)
  • 5700-49-2 (di-hydriodide)
  • 624-59-9 (di-hydrobromide)

System Generated Number

  • 0000107153

Structure Descriptors

InChI

1S/C2H8N2/c3-1-2-4/h1-4H2

InChIKey

PIICEJLVQHRZGT-UHFFFAOYSA-N

Smiles

C(CN)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 100mg/kg (100mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1295, 1935.
guinea pig LD50 oral 470mg/kg (470mg/kg) GASTROINTESTINAL: OTHER CHANGES

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.
human TCLo inhalation 200ppm (200ppm) PERIPHERAL NERVE AND SENSATION: PARESTHESIS AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 9, Pg. 223, 1954.
mouse LC50 inhalation 300mg/m3 (300mg/m3)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 66, 1982.
mouse LD50 intraperitoneal 200mg/kg (200mg/kg)   Chimica Therapeutica. Vol. 4, Pg. 136, 1969.
mouse LD50 oral 1gm/kg (1000mg/kg) BEHAVIORAL: ATAXIA Meditsina Truda i Promyshlennaya Ekologiya. Industrial Medicine and Ecology. Vol. (1), Pg. 38, 1997.
rabbit LD50 skin 730uL/kg (0.73mL/kg)   AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
rabbit LDLo subcutaneous 500mg/kg (500mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1295, 1935.
rat LCLo inhalation 4000ppm/8H (4000ppm)   AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
rat LD50 intraperitoneal 76mg/kg (76mg/kg)   Toxicology and Applied Pharmacology. Vol. 21, Pg. 454, 1972.
rat LD50 oral 1200mg/kg (1200mg/kg) BEHAVIORAL: ATAXIA Meditsina Truda i Promyshlennaya Ekologiya. Industrial Medicine and Ecology. Vol. (1), Pg. 38, 1997.
rat LD50 subcutaneous 300mg/kg (300mg/kg)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 66, 1982.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 11.1 deg C   EXP
Boiling Point 117 deg C   EXP
pKa Dissociation Constant 9.922 (none)   EXP
log P (octanol-water) -2.04E+00 (none)   EXP
Water Solubility 1.00E+06 mg/L   EXP
Vapor Pressure 12 mm Hg 25 EXP
Henry's Law Constant 1.73E-09 atm-m3/mole 25 EXP
Atmospheric OH Rate Constant 6.34E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.