Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Propargyl alcohol
RN: 107-19-7
UNII: E920VF499L
InChIKey: TVDSBUOJIPERQY-UHFFFAOYSA-N

Note

  • Irreversibly inactivates alcohol oxidase.

Molecular Formula

  • C3-H4-O

Molecular Weight

  • 56.0636
 

Classification Codes

Classification Codes

  • Agricultural Chemical
  • Mutation Data
  • Tumor Data

Superlist Classification Codes

  • Reportable Quantity (RQ) = 1000 lb
  • TWA (1 ppm); skin

Names and Synonyms

Name of Substance

  • Propargyl alcohol

Synonyms

  • 1-Hydroxy-2-propyne
  • 1-Propyn-3-ol
  • 2-Propyn-1-ol
  • 2-Propynyl alcohol
  • 3-Hydroxy-1-propyne
  • 3-Propynol
  • 4-01-00-02214 (Beilstein Handbook Reference)
  • Acetylene carbinol
  • Acetylenylcarbinol
  • Agrisynth PA
  • AI3-24359
  • BRN 0506003
  • CCRIS 6781
  • EC 203-471-2
  • EINECS 203-471-2
  • Ethynyl carbinol
  • Ethynylcarbinol
  • HSDB 6054
  • Methanol, ethynyl-
  • NSC 8804
  • Propargyl alcohol
  • Propiolic alcohol
  • Propynyl alcohol
  • RCRA waste number P102
  • UNII-E920VF499L

Systematic Names

  • 2-Propyn-1-ol
  • Prop-2-yn-1-ol
  • Propargyl alcohol

Superlist Names

  • 2-Propyn-1-ol
  • NA1986
  • Propargyl alcohol
  • Propargyl alcohol [NA1986] [Flammable liquid]
  • RCRA waste no. P102

Registry Numbers

CAS Registry Number

  • 107-19-7

FDA UNII

  • E920VF499L

System Generated Number

  • 0000107197

Structure Descriptors

InChI

1S/C3H4O/c1-2-3-4/h1,4H,3H2

InChIKey

TVDSBUOJIPERQY-UHFFFAOYSA-N

Smiles

C(#C)CO

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 60mg/kg (60mg/kg)   The Threshold Limit Values Vol. 4, Pg. 346, 1980.
mammal (species unspecified) LC50 inhalation 3gm/m3 (3000mg/m3)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988.
mammal (species unspecified) LD50 oral 50mg/kg (50mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988.
mammal (species unspecified) LD50 unreported 53mg/kg (53mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 51(5), Pg. 61, 1986.
mouse LC50 inhalation 2000mg/m3/2H (2000mg/m3) BEHAVIORAL: EXCITEMENT

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 8, Pg. 97, 1966.
mouse LD50 oral 50mg/kg (50mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BLOOD: HEMORRHAGE
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 8, Pg. 97, 1966.
rabbit LD50 skin 16mg/kg (16mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4672, 1982.
rabbit LDLo subcutaneous 25mg/kg (25mg/kg)   "Zur Pharmakologie Ungesattigter Alkohole, Dissertation," Bock, H., Pharmakologischen Institu der Universitat Breslau, Poland, 1930Vol. -, Pg. -, 1930.
rat LC50 inhalation 873ppm/2H (873ppm)   GAF Material Safety Data Sheet.
rat LD50 oral 20mg/kg (20mg/kg)   "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4672, 1982.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -5.18E+01 deg C   EXP
Boiling Point 113.6 deg C   EXP
log P (octanol-water) -0.38 (none)   EXP
Water Solubility 1.00E+06 mg/L 20 EXP
Vapor Pressure 15.6 mm Hg 25 EXP
Henry's Law Constant 1.15E-06 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 1.04E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.