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Substance Name: Glyphosate [ANSI:BSI:ISO]
RN: 1071-83-6
UNII: 4632WW1X5A
InChIKey: XDDAORKBJWWYJS-UHFFFAOYSA-N

Note

  • Active cpd in herbicidal formulation Roundup; inhibits EC 2.5.1.19, 5-enolpyruvylshikimate-3-phosphate synthase.

Molecular Formula

  • C3-H8-N-O5-P

Molecular Weight

  • 169.0722
 

Classification Codes

Classification Codes

  • Agricultural Chemical
  • Anti-Infective Agents
  • Antifungal Agents
  • Enzyme Inhibitors
  • Herbicide
  • Herbicides
  • Human Data
  • Mutation Data
  • Pesticides
  • Tumor Data
  • Uncoupling Agents

Superlist Classification Code

  • Overall Carcinogenic Evaluation: Group 2A

Names and Synonyms

Results Name

  • Glyphosate [ANSI:BSI:ISO]

Name of Substance

  • Glyphosate
  • Glyphosate [ANSI:BSI:ISO]

Synonyms

  • Accord
  • Atila
  • BRN 2045054
  • Buccaneer
  • Buccaneer Plus
  • C-K Yuyos FAV
  • Carboxymethylaminomethanephosphinic acid
  • Caswell No. 661A
  • CCRIS 1587
  • CP 67573
  • EINECS 213-997-4
  • EPA Pesticide Chemical Code 417300
  • Folusen
  • Forsat
  • Glialka
  • Glialka 36
  • Glifoglex
  • Glifosan 747
  • Gliz
  • Gliz 480CS
  • Glyfos
  • GlyGran
  • Glyphodin A
  • Glyphomax
  • Glyphosate
  • Glyphosate CT
  • Glyphosphate
  • Ground Bio
  • Herbatop
  • HM 2028
  • Hockey
  • HSDB 3432
  • Kickdown
  • Klinik
  • Lancer
  • Lancer (herbicide)
  • Leone
  • MON 2139
  • MON 3539
  • MON 6000
  • N-(Phosphonomethyl)glycine
  • N-Phosphomethylglycine
  • N-Phosphonomethylglycine
  • NSC 151063
  • Phorsat
  • Phosphonomethylglycine
  • Phosphonomethyliminoacetic acid
  • Pondmaster
  • Rebel Garden
  • Roundup Max
  • Safal
  • Scout
  • Silglif
  • UNII-4632WW1X5A

Systematic Names

  • Glycine, N-(phosphonomethyl)-
  • Glyphosate
  • Glyphosphate

Superlist Name

  • Glyphosate

Registry Numbers

CAS Registry Number

  • 1071-83-6

FDA UNII

  • 4632WW1X5A

Other Registry Numbers

  • 1585457-94-8
  • 37337-60-3
  • 42618-09-7
  • 75241-08-6

Related Registry Numbers

  • 34494-03-6 (mono-hydrochloride salt)
  • 40465-66-5 (mono-ammonium salt)
  • 70393-85-0 (hydrochloride salt)

System Generated Number

  • 0001071836

Structure Descriptors

InChI

1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)

InChIKey

XDDAORKBJWWYJS-UHFFFAOYSA-N

Smiles

C(C(=O)O)NCP(=O)(O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man LDLo oral 2143mg/kg (2143mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

LUNGS, THORAX, OR RESPIRATION: FIBROSIS (INTERSTITIAL)

LUNGS, THORAX, OR RESPIRATION: FIBROSING ALVEOLITIS
Journal of Toxicology, Clinical Toxicology. Vol. 29, Pg. 91, 1991.
man TDLo oral 1214mg/kg (1214mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

CARDIAC: CHANGE IN RATE
Human & Experimental Toxicology. Vol. 10, Pg. 103, 1991.
mouse LD50 intraperitoneal 130mg/kg (130mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toxicology Letters. Vol. 1000(Sp,
mouse LD50 oral 1568mg/kg (1568mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toxicology and Applied Pharmacology. Vol. 45, Pg. 319, 1978.
quail LD50 oral > 4640mg/kg (4640mg/kg)   Pesticide Manual. Vol. 9, Pg. 459, 1991.
rabbit LD50 oral 3800mg/kg (3800mg/kg)   Pesticide & Toxic Chemical News. Vol. 7, Pg. 6, 1978.
rabbit LD50 skin 7940mg/kg (7940mg/kg)   "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc of Chemistry, 1983-86Vol. A222, Pg. 1984,
rat LC50 inhalation > 12200mg/m3/4 (12200mg/m3)   "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc of Chemistry, 1983-86Vol. A222, Pg. 1984,
rat LD50 intraperitoneal 235mg/kg (235mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toxicology Letters. Vol. 1000(Sp,
rat LD50 oral 4873mg/kg (4873mg/kg)   Toxicology and Applied Pharmacology. Vol. 45, Pg. 319, 1978.
rat LD50 oral 4873mg/kg (4873mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Toxicology and Applied Pharmacology. Vol. 45, Pg. 319, 1978.
women LDLo oral 4gm/kg (4000mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)
Journal of Toxicology, Clinical Toxicology. Vol. 29, Pg. 91, 1991.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 189.5 deg C   EXP
pKa Dissociation Constant 0.8 (none)   EXP
log P (octanol-water) -4.00E+00 (none)   EXP
Water Solubility 1.20E+04 mg/L 25 EXP
Vapor Pressure 2.89E-10 mm Hg 25 EST
Henry's Law Constant 4.08E-19 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 7.90E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.