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Substance Name: Spike glycoprotein, coronavirus
RN: 107476-75-5


  • A class I viral fusion protein that forms the characteristic spikes, or peplomers, found on the viral surface that mediate virus attachment, fusion, and entry into the host cell. During virus maturation, it is cleaved into two subunits: S1, which binds to receptors in the host cell, and S2, which mediates membrane fusion.

Molecular Formula

  • Unspecified
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Names and Synonyms

Name of Substance

  • Spike glycoprotein, coronavirus

MeSH Heading

  • Spike Glycoprotein, Coronavirus


  • E2 apike glycoprotein, coronavirus
  • E2 glycoprotein, transmissible gastroenteritis coronavirus
  • E2 peplomer protein (tgev)
  • Glycoprotein S, coronavirus
  • Mhv surface projection glycoprotein
  • Mouse hepatitis virus (mhv) S protein
  • Peplomer protein, mouse hepatitis virus (mhv)
  • S Gene product, coronavirus
  • S Protein, avian infectious bronchitis virus
  • S Protein, canine coronavirus (ccv)
  • S Protein, feline infectious peritonitis virus (fipv)
  • S Protein, porcine respiratory coronavirus (prcv)
  • S Protein, transmissible gastroenteritis virus (tgev)
  • Spike glycoprotein S1, coronavirus
  • Spike glycoprotein, bovine coronavirus (bcv)
  • Spike glycoprotein, human coronavirus (hcv)
  • Spike gp S1, cor
  • Spike protein S2, coronavirus
  • Spike protein, coronavirus

Systematic Name

  • Glycoprotein S (JHM virus clone pJS92/pJS112/pJMS1010 protein moiety reduced)

Registry Numbers

CAS Registry Number

  • 107476-75-5

System Generated Number

  • 0107476755