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Substance Name: Imiphos
RN: 1078-79-1
UNII: 83TB06MD0K
InChIKey: FJYYWRQKUXJNMW-UHFFFAOYSA-N

Molecular Formula

  • C8-H16-N3-O-P-S

Molecular Weight

  • 233.2744
 
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Names and Synonyms

Name of Substance

  • Imiphos

Synonyms

  • BRN 1214283
  • Imiphos
  • Marcophan
  • Marcophane
  • Markofane
  • UNII-83TB06MD0K

Systematic Names

  • 3-(Bis(1-aziridinyl)phosphinyl)-2-methylthiazolidine
  • Phosphine oxide, bis(1-aziridinyl)(2-methyl-3-thiazolidinyl)-

Registry Numbers

CAS Registry Number

  • 1078-79-1

FDA UNII

  • 83TB06MD0K

System Generated Number

  • 0001078791

Structure Descriptors

InChI

1S/C8H16N3OPS/c1-8-11(6-7-14-8)13(12,9-2-3-9)10-4-5-10/h8H,2-7H2,1H3

InChIKey

FJYYWRQKUXJNMW-UHFFFAOYSA-N

Smiles

CC1SCCN1P(=O)(N2CC2)N3CC3

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 142mg/kg (142mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: ATAXIA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
"Imifos," Giller, S.A., ed., Izd, Riga, USSR, 1968Vol. -, Pg. 129, 1968.
mouse LD50 oral 225mg/kg (225mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: ATAXIA
"Imifos," Giller, S.A., ed., Izd, Riga, USSR, 1968Vol. -, Pg. 129, 1968.
rat LD50 intraperitoneal 18700ug/kg (18.7mg/kg) BLOOD: LEUKOPENIA Farmakologiya i Toksikologiya Vol. 37, Pg. 464, 1974.