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Substance Name: Deanol [BAN]
RN: 108-01-0
UNII: 2N6K9DRA24
InChIKey: UEEJHVSXFDXPFK-UHFFFAOYSA-N

Note

  • An antidepressive agent that has also been used in the treatment of movement disorders. The mechanism of action is not well understood.

Molecular Formula

  • C4-H11-N-O

Molecular Weight

  • 89.1369
 

Classification Codes

  • Anti-Dyskinesia Agents
  • Antidepressive Agents
  • Central Nervous System Agents
  • Psychotropic Drugs
  • Skin / Eye Irritant

Names and Synonyms

Name of Substance

  • 2-Dimethylaminoethanol
  • Deanol
  • Deanol [BAN]

MeSH Heading

  • Deanol

Synonyms

  • (2-Hydroxyethyl)dimethylamine
  • 2-(Dimethylamino)-1-ethanol
  • 2-(N,N-Dimethylamino)ethanol
  • 2-Dimethylaminoethanol
  • 2-Dwumetyloaminoetanolu
  • 2-Dwumetyloaminoetanolu [Polish]
  • 4-11-00-00122 (Beilstein Handbook Reference)
  • AI3-09209
  • Amietol M 21
  • beta-Dimethylaminoethyl alcohol
  • beta-Hydroxyethyldimethylamine
  • Bimanol
  • BRN 1209235
  • CCRIS 4802
  • Deanol
  • Dimethyl(2-hydroxyethyl)amine
  • Dimethyl(hydroxyethyl)amine
  • Dimethylaethanolamin
  • Dimethylaethanolamin [German]
  • Dimethylaminoaethanol
  • Dimethylaminoaethanol [German]
  • Dimethylaminoethanol
  • Dimethylethanolamine
  • Dimethylmonoethanolamine
  • DMAE
  • DMEA
  • EC 203-542-8
  • EINECS 203-542-8
  • Ethanol, 2-(dimethylamino)-
  • HSDB 1329
  • Kalpur P
  • Liparon
  • N,N-Dimethyl-2-aminoethanol
  • N,N-Dimethyl-2-hydroxyethylamine
  • N,N-Dimethyl-N-(2-hydroxyethyl)amine
  • N,N-Dimethyl-N-(beta-hydroxyethyl)amine
  • N,N-Dimethylaminoethanol
  • N,N-Dimethylethanolamine
  • N-(2-Hydroxyethyl)dimethylamine
  • N-Dimethylaminoethanol
  • Norcholine
  • NSC 2652
  • Propamine A
  • Texacat DME
  • UNII-2N6K9DRA24
  • Varesal

Systematic Names

  • 2-Dimethylaminoethanol
  • Ethanol, 2-(dimethylamino)-

Superlist Names

  • 2-(Dimethylamino) ethanol
  • 2-(Dimethylamino)ethanol
  • 2-Dimethylaminoethanol [UN2051] [Corrosive]
  • Dimethylaminoethanol
  • Dimethylethanolamine
  • Ethanol, 2-(dimethylamino)-
  • UN2051

Registry Numbers

CAS Registry Number

  • 108-01-0

FDA UNII

  • 2N6K9DRA24

Other Registry Numbers

  • 116134-09-9
  • 156681-25-3

System Generated Number

  • 0000108010

Structure Descriptors

InChI

1S/C4H11NO/c1-5(2)3-4-6/h6H,3-4H2,1-2H3

InChIKey

UEEJHVSXFDXPFK-UHFFFAOYSA-N

Smiles

CN(C)CCO

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LDLo intraperitoneal 450mg/kg (450mg/kg)   Proceedings of the Society for Experimental Biology and Medicine. Vol. 85, Pg. 642, 1954.
mouse LC50 inhalation 3250mg/m3 (3250mg/m3) SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 14(11), Pg. 52, 1970.
mouse LD50 intraperitoneal 234mg/kg (234mg/kg) BEHAVIORAL: ATAXIA Journal of Pharmacology and Experimental Therapeutics. Vol. 94, Pg. 249, 1948.
mouse LD50 subcutaneous 961mg/kg (961mg/kg) BEHAVIORAL: COMA

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

BEHAVIORAL: TREMOR
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 225, Pg. 428, 1955.
rabbit LD50 skin 1370uL/kg (1.37mL/kg)   AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
rat LC50 inhalation 1641ppm/4H (1641ppm) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Fundamental and Applied Toxicology. Vol. 9, Pg. 512, 1987.
rat LD50 intraperitoneal 1080mg/kg (1080mg/kg)   Toxicology and Applied Pharmacology. Vol. 12, Pg. 486, 1968.
rat LD50 oral 2gm/kg (2000mg/kg)   Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. Vol. 20, Pg. 393, 1974.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -5.90E+01 deg C   EXP
Boiling Point 134 deg C   EXP
pKa Dissociation Constant 9.31 (none) 20 EXP
log P (octanol-water) -0.940 (none)   EST
Water Solubility 1.00E+06 mg/L   EXP
Vapor Pressure 3.18 mm Hg 25 EXP
Henry's Law Constant 3.73E-07 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 9.00E-11 cm3/molecule-sec 25 EXP

Physical property data is provided to ChemIDplus by SRC, Inc.