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Substance Name: Maleic anhydride
RN: 108-31-6
UNII: V5877ZJZ25
InChIKey: FPYJFEHAWHCUMM-UHFFFAOYSA-N

Note

  • Used in copolymerization reactions, in the Diels-Alder(diene)synthesis, in the preparation of resins, pharmaceuticals and agricultural chemicals. It is a powerful irritant and causes burns.

Molecular Formula

  • C4-H2-O3

Molecular Weight

  • 98.0568
 

Classification Codes

Classification Codes

  • Mutation Data
  • Reproductive Effect
  • Skin / Eye Irritant
  • Tumor Data

Superlist Classification Codes

  • Reportable Quantity (RQ) = 5000 lb
  • TWA (0.1 ppm); Sensitizer; Not classifiable as a human carcinogen
  • TWA 0.25 ppm (1 mg/m3)

Names and Synonyms

Name of Substance

  • Maleic anhydride

MeSH Heading

  • Maleic Anhydrides

Synonyms

  • 2,5-Furandione
  • 5-17-11-00055 (Beilstein Handbook Reference)
  • AI3-24283
  • Anhydrid kyseliny maleinove
  • Anhydrid kyseliny maleinove [Czech]
  • BRN 0106909
  • CCRIS 2941
  • cis-Butenedioic anhydride
  • Dihydro-2,5-dioxofuran
  • EC 203-571-6
  • EINECS 203-571-6
  • HSDB 183
  • Maleic acid anhydride
  • Maleic anhydride
  • Maleinanhydrid
  • Maleinanhydrid [Czech]
  • NSC 137651
  • RCRA waste number U147
  • Toxilic anhydride
  • UNII-V5877ZJZ25

Systematic Names

  • 2,5-Furandione
  • Maleic anhydride

Superlist Names

  • 2,5-Furandione
  • Maleic anhydride
  • Maleic anhydride [UN2215] [Corrosive]
  • RCRA waste no. U147
  • UN2215

Registry Numbers

CAS Registry Number

  • 108-31-6

FDA UNII

  • V5877ZJZ25

Other Registry Numbers

  • 1190407-73-8
  • 1229972-04-6
  • 1380217-40-2
  • 184288-31-1

System Generated Number

  • 0000108316

Structure Descriptors

InChI

1S/C4H2O3/c5-3-1-2-4(6)7-3/h1-2H

InChIKey

FPYJFEHAWHCUMM-UHFFFAOYSA-N

Smiles

C1(OC(=O)C=C1)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 390mg/kg (390mg/kg)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 79, 1982.
guinea pig LD50 skin > 20gm/kg (20000mg/kg)   Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974Vol. 17JUN1974,
mouse LD50 oral 465mg/kg (465mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 13(4), Pg. 42, 1969.
rabbit LD50 oral 875mg/kg (875mg/kg)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 79, 1982.
rabbit LD50 skin 2620mg/kg (2620mg/kg)   Toxicology and Applied Pharmacology. Vol. 42, Pg. 417, 1977.
rat LD50 intraperitoneal 97mg/kg (97mg/kg)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 79, 1982.
rat LD50 oral 400mg/kg (400mg/kg)   Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974Vol. 17JUN1974,

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 52.8 deg C   EXP
Boiling Point 202 deg C   EXP
log P (octanol-water) 1.620 (none)   EST
Water Solubility 4910 mg/L 25 EST
Henry's Law Constant 3.93E-06 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 1.45E-12 cm3/molecule-sec 23 EXP

Physical property data is provided to ChemIDplus by SRC, Inc.