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Substance Name: Profenamine hydrochloride
RN: 1094-08-2
UNII: O00T1I1VRN
InChIKey: VXPCQISYVPFYRK-UHFFFAOYSA-N

Classification Codes

  • Antiparkinsonian
  • Drug / Therapeutic Agent

Molecular Formula

  • C19-H24-N2-S.Cl-H

Molecular Weight

  • 348.9395
 
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Names and Synonyms

Results Name

  • Profenamine hydrochloride

Name of Substance

  • Ethopropazine hydrochloride [USP]

Synonyms

  • 10-(2-(Diethylamino)propyl)phenothiazine monohydrochloride
  • 10-Phenothiazineethylamine, N,N-diethyl-alpha-methyl-, hydrochloride
  • Dibutil
  • EINECS 214-134-4
  • Ethopropazine HCl
  • Ethopropazine hydrochloride
  • Isothazine hydrochloride
  • l-10-(2-Diethylaminopropyl)phenothiazine hydrochloride
  • Lysivane
  • Lysivane hydrochloride
  • NSC 169467
  • NSC 64074
  • Pardisol
  • Parfezin
  • Parphezein
  • Parphezin
  • Parsidol
  • Parsidol (VAN)
  • Profenamine hydrochloride
  • Profenamine monohydrochloride
  • UNII-O00T1I1VRN

Systematic Names

  • 10H-Phenothiazine-10-ethanamine, N,N-diethyl-alpha-methyl-, monohydrochloride
  • N,N-Diethyl-alpha-methyl-10H-phenothiazine-10-ethylamine monohydrochloride
  • Phenothiazine, 10-(2-(diethylamino)propyl)-, monohydrochloride

Registry Numbers

CAS Registry Number

  • 1094-08-2

FDA UNII

  • O00T1I1VRN

System Generated Number

  • 0001094082

Molecular Formulas

Molecular Formula

  • C19-H24-N2-S.Cl-H

Molecular Formula Fragments

  • C19-H24-N2-S
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C19H24N2S.ClH/c1-4-20(5-2)15(3)14-21-16-10-6-8-12-18(16)22-19-13-9-7-11-17(19)21;/h6-13,15H,4-5,14H2,1-3H3;1H

InChIKey

VXPCQISYVPFYRK-UHFFFAOYSA-N

Smiles

CCN(CC)C(C)CN1c2ccccc2Sc3c1cccc3.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 160mg/kg (160mg/kg)   Drugs in Japan Vol. -, Pg. 1041, 1990.
mouse LD50 intravenous 32mg/kg (32mg/kg)   U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00853,
mouse LD50 oral 650mg/kg (650mg/kg)   Schweizerische Medizinische Wochenschrift. Vol. 88, Pg. 713, 1958.
mouse LD50 subcutaneous 670mg/kg (670mg/kg) KIDNEY, URETER, AND BLADDER: HEMATURIA British Journal of Pharmacology and Chemotherapy. Vol. 14, Pg. 559, 1959.
rat LD50 intraperitoneal 390mg/kg (390mg/kg)   Drugs in Japan Vol. -, Pg. 1041, 1990.
rat LD50 oral 1700mg/kg (1700mg/kg)   Drugs in Japan Vol. -, Pg. 1041, 1990.
rat LD50 subcutaneous 3300mg/kg (3300mg/kg)   Drugs in Japan Vol. -, Pg. 1041, 1990.