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Substance Name: Crenezumab [USAN:INN]
RN: 1095207-05-8
UNII: O8AS5277H0


  • Humanized antibody against human 1-40 and 1-42 beta amyloid.

Molecular Formula

  • C6348-H9796-N1688-O2010-S44

Classification Code

  • Treatment of Alzheimer's Disease
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Links to Resources

Names and Synonyms

Name of Substance

  • Crenezumab [USAN:INN]


  • Crenezumab
  • Immunoglobulin G4, anti-(human beta-amyloid proteins 40 and 42 (beta-APP40, beta-APP42)); humanized mouse monoclonal MABT5102A gamma4 heavy chain (des-439- lysine(CH3(sup 107)K)(220-proline(H(sup 10)S>P))human constant gamma4) (126-219')-disulfide with humanized mouse monoclonal AMG162 kappa light chain, dimer (218-218'':221-221'')- bisdisulfide
  • MABT5102A
  • UNII-O8AS5277H0

Systematic Name

  • Immunoglobulin G4, anti-(human 1-40-beta-amyloid/human 1-42-beta-amyloid) (human-mouse monoclonal MABT5102A heavy chain), disulfide with human-mouse monoclonal MABT5102A light chain, dimer

Registry Numbers

CAS Registry Number

  • 1095207-05-8


  • O8AS5277H0

System Generated Number

  • 1095207058