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Substance Name: Granisetron [USAN:INN:BAN:JAN]
RN: 109889-09-0
UNII: WZG3J2MCOL
InChIKey: MFWNKCLOYSRHCJ-BTTYYORXSA-N

Note

  • A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapy patients.

Molecular Formula

  • C18-H24-N4-O

Molecular Weight

  • 312.4146
 

Classification Codes

  • Anti-Emetic
  • Antiemetics
  • Autonomic Agents
  • Central Nervous System Agents
  • Gastrointestinal Agents
  • Neurotransmitter Agents
  • Peripheral Nervous System Agents
  • Serotonin Agents
  • Serotonin Antagonists

Names and Synonyms

Name of Substance

  • Granisetron
  • Granisetron [USAN:INN:BAN:JAN]

MeSH Heading

  • Granisetron

Synonyms

  • 1-Methyl-N-(9-methyl-endo-9-azabicyclo(3.3.1)non-3-yl)-1H-indazole-3-carboxamide
  • 1H-Indazole-3-carboxamide, 1-methyl-N-(9-methyl-9-azabicyclo(3.3.1)non-3-yl)-, endo-
  • APF 530
  • APF530
  • BRL 43694
  • BRL 43964
  • Granisetron
  • Granisetronum
  • Granisetronum [INN-Latin]
  • Kevatril
  • Sancuso
  • Sustol
  • UNII-WZG3J2MCOL

Systematic Name

  • 1H-Indazole-3-carboxamide, 1-methyl-N-(9-methyl-9-azabicyclo(3.3.1)non-3-yl)-, endo-

Registry Numbers

CAS Registry Number

  • 109889-09-0

FDA UNII

  • WZG3J2MCOL

Other Registry Number

  • 121061-98-1

Related Registry Number

  • 107007-99-8 (mono-hydrochloride)

System Generated Number

  • 0109889090

Structure Descriptors

InChI

InChI=1S/C18H24N4O/c1-21-13-6-5-7-14(21)11-12(10-13)19-18(23)17-15-8-3-4-9-16(15)22(2)20-17/h3-4,8-9,12-14H,5-7,10-11H2,1-2H3,(H,19,23)/t12-,13+,14-

InChIKey

MFWNKCLOYSRHCJ-BTTYYORXSA-N

Smiles

CN1[C@@H]2CCC[C@H]1C[C@H](C2)NC(=O)c3nn(C)c4ccccc34