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Substance Name: Putrescine
RN: 110-60-1
UNII: V10TVZ52E4
InChIKey: KIDHWZJUCRJVML-UHFFFAOYSA-N

Note

  • A toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine.

Classification Codes

  • Mutation Data
  • Reproductive Effect

Molecular Formula

  • C4-H12-N2

Molecular Weight

  • 88.1528
 
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Names and Synonyms

Name of Substance

  • Putrescine

MeSH Heading

  • Putrescine

Synonyms

  • 1,4-Butylenediamine
  • 1,4-Diaminobutane
  • 1,4-Tetramethylenediamine
  • 4-04-00-01283 (Beilstein Handbook Reference)
  • AI3-25444
  • BRN 0605282
  • Butylenediamine
  • CCRIS 6751
  • EC 203-782-3
  • EINECS 203-782-3
  • HSDB 7865
  • NSC 60545
  • Putrescin
  • Putrescine
  • Tetramethyldiamine
  • Tetramethylenediamine
  • UNII-V10TVZ52E4

Systematic Names

  • 1,4-Butanediamine
  • Putrescine
  • Tetramethylenediamine

Registry Numbers

CAS Registry Number

  • 110-60-1

FDA UNII

  • V10TVZ52E4

System Generated Number

  • 0000110601

Structure Descriptors

InChI

1S/C4H12N2/c5-3-1-2-4-6/h1-6H2

InChIKey

KIDHWZJUCRJVML-UHFFFAOYSA-N

Smiles

C(CCN)CN

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1750mg/kg (1750mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Farmakologiya i Toksikologiya Vol. 18(6), Pg. 9, 1955.
mouse LDLo oral 1600mg/kg (1600mg/kg)   Archives of Environmental Contamination and Toxicology. Vol. 14, Pg. 111, 1985.
rabbit LD50 skin 1576mg/kg (1576mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"

KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
National Technical Information Service. Vol. OTS0538638,
rabbit LDLo intravenous 80mg/kg (80mg/kg)   Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 83, Pg. 481, 1920.
rabbit LDLo oral 1600mg/kg (1600mg/kg)   Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 83, Pg. 481, 1920.
rabbit LDLo rectal 400mg/kg (400mg/kg)   Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 83, Pg. 481, 1920.
rabbit LDLo subcutaneous 1gm/kg (1000mg/kg)   Zeitschrift fuer Experimentelle Pathologie und Therapie. Vol. 17, Pg. 59, 1915.
rat LD50 oral 463mg/kg (463mg/kg) KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION

SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
National Technical Information Service. Vol. OTS0538638,
rat LDLo subcutaneous 1gm/kg (1000mg/kg)   Zeitschrift fuer Experimentelle Pathologie und Therapie. Vol. 17, Pg. 59, 1915.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 27.5 deg C   EXP
Boiling Point 158.5 deg C   EXP
pKa Dissociation Constant 10.8 (none) 20 EXP
log P (octanol-water) -0.7 (none)   EXP
Water Solubility 1.00E+06 mg/L 25 EST
Vapor Pressure 4.120 mm Hg 25 EST
Henry's Law Constant 1.82E-09 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 6.62E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.